Results 41 to 50 of about 4,172 (223)

Protein promiscuity in H2O2 signaling [PDF]

, 2019
Significance: Decrypting the cellular response to oxidative stress relies on a comprehensive understanding of the redox signaling pathways stimulated under oxidizing conditions.
Bodra, Nandita, De Smet, Barbara, Ezerina, Daria, Huang, Jingjing, Lewandowska, Aleksandra, Messens, Joris, Pedre, Brandan, Rosado, Leonardo Astolfi, Tossounian, Maria-Armineh, Van Breusegem, Frank, Young, David   +10 more
core   +2 more sources

A Simple, Proficient and Green Approach for the Synthesis of 1,8-Dioxo-octahydroxanthenes Catalyzed by Cerium(IV) Ammonium Nitrate in Aqueous Media

Orbital: The Electronic Journal of Chemistry, 2014
Various biologically important 1,8-dioxo-“octahydroxanthene derivatives” have been efficiently synthesized in excellent yields using catalytic amounts of cerium(IV) ammonium nitrate (CAN) in water.
Shitole Nana Vikram, Nana V. Shitole, Gopal K. Kakde   +2 more
doaj   +1 more source

A facile microwave assisted one-pot synthesis of novel 1-methylhexahydroquinazolin-5(6H)-ones and bis-1-methylhexahydroquinazolin-5(6H)-ones

Orbital: The Electronic Journal of Chemistry, 2011
Novel hexahydroquinazolin-5(6H)-ones 3a-j have been synthesized in good yields by the reaction of enaminones 2a-b with primary amines and formaldehyde under the influence microwaves.
Madhusudhan Saha, Enamul Karim, Jai Narain Vishwakarma, Rishanlang Nongkhlaw   +3 more
doaj   +1 more source

Asymmetric Transformations of α,β‐Unsaturated Oxazolidinones Catalyzed by C2‐Symmetric Chiral Iron Triad Complexes

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley   +1 more source

Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating

Beilstein Journal of Organic Chemistry, 2012
The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a ...
Kamal Usef Sadek, Ramadan Ahmed Mekheimer, Tahany Mahmoud Mohamed, Moustafa Sherief Moustafa, Mohamed Hilmy Elnagdi   +4 more
doaj   +1 more source

β‐Triketone‐Based Ionizable Cationic Lipids Synthesized via Click Chemistry for siRNA Delivery

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study innovatively applies β‐triketone‐based click chemistry in the synthesis of ionizable cationic lipids (ICLs), which allows the generation of a lipid library in large quantities and in a short time. The ICLs identified achieved effective lipid nanoparticles‐mediated hepatic gene silencing in vivo using siRNA, and computational simulations are ...
Huatian Li, Haocheng Tang, Yiqing Mu, Shangyu Chen, Paul Edward Floreancig, Junmei Wang, Yixian Huang, Song Li   +7 more
wiley   +1 more source

Investigation of efficient synthesis of 1, 8-dioxo-octahydroxanthene derivatives under solvent-free grinding method [PDF]

, 2013
In these studies, we had observed polyaniline (PANI) supported p-toluene sulfonic acid (TsOH) and FeCl3 (PANI- TsOH, PANI-FeCl3) as excellent reusable solid acid catalysts for the synthesis of 1, 8-dioxo-octahydroxanthene derivatives 4(a-g) under solvent-
P. Dutta, P. Sarma, R. Borah
core   +1 more source

Direct Mechanoorganocatalysis via Surface Functionalization of Milling Reactors With Amine Functions

ChemistryEurope, Volume 4, Issue 5, May 2026.
Surface functionalization of milling jars in epoxy resin furnished reactive milling jars, able to perform direct mechanoorganocatalysis with high efficiency, recyclability, and simplified purification. This proof of concept was applied successfully to base‐catalyzed Knoevenagel condensation and multicomponent reactions.
Joao Tanepau, Maxime Provost, Marie Gressier, Marie‐Joëlle Menu, Sandrine Duluard, Frédéric Lamaty, Julien Pinaud, Xavier Bantreil   +7 more
wiley   +1 more source

Alum promoted synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives in water

Orbital: The Electronic Journal of Chemistry, 2012
A new and efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes using alum [KAl(SO4)2.12H2O] as catalyst was ...
Balaji Rajendra Madje, Jagdish V. Bharad, Milind B. Ubale, Murlidhar S. Shingare   +3 more
doaj   +1 more source

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC‐T's

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A multidisciplinary approach based on organic synthesis supported by quantum mechanical calculations, efficient phosphorylation methods, affinity studies using conventional techniques and saturation transfer difference nuclear magnetic resonance, together with molecular dynamics simulations, has enabled the preparation of nucleotide analogs with ...
Pedro Merino, Veronica Juste, Alejandro Montesa, Sandra Pereira, Sara Orta, Manuel Pedrón, Ana I. Jiménez, Sonsoles Martín‐Santamaría, Ramón Hurtado‐Guerrero, Ignacio Delso, Tomás Tejero   +10 more
wiley   +1 more source