Results 11 to 20 of about 326 (161)

One-pot and facile synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones using nano-NiO under solvent-free conditions [PDF]

open access: yesشیمی کاربردی روز, 2016
In this article, nano-NiO as a heterogenuos and recyclable catalyst has been used for the synthesis of 1H-Pyrazolo[1,2-b]Phthalazine-5,10-Diones by the reaction of malononitrile, aldehydes and phthalhydrazide under solvent-free conditions. Short reaction
بهروز ملکی   +3 more
doaj   +2 more sources

Alum promoted synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives in water

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
A new and efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes using alum [KAl(SO4)2.12H2O] as catalyst was ...
Balaji Rajendra Madje   +3 more
doaj   +2 more sources

Recruitment of macrophages and bone marrow stem cells to regenerating liver promoted by sodium phthalhydrazide in mice [PDF]

open access: yesBiomedicine & Pharmacotherapy, 2019
Pharmacological interventions which could be hepatoprotective, depending on bioavailability, anti-inflammatory and macrophage-targeting potential of drugs, are still at early preclinical stages. Existing evidence from many animal models of liver injury, as well as from human data, indicate that pharmacological and/or phytochemical interventions have ...
Danilova, I. G.   +5 more
openaire   +4 more sources

Implementation of a combinatorial cleavage and deprotection scheme. 1. Synthesis of phthalhydrazide libraries

open access: yesTetrahedron Letters, 1996
Abstract Phthalhydrazide libraries are synthesized in solution from substituted hydrazines and phthalimides in several different library formats including single compounds, indexed sub-libraries and a full library. When carried out during solid-phase synthesis, this combinatorial cleavage and deprotection scheme offers the possibility for generating ...
Nielsen, John, Rasmussen, P. H.
openaire   +3 more sources

Azolyacetones as Precursors to Indoles and Naphthofurans Facilitated by Microwave Irradiation with Simultaneous Cooling

open access: yesMolecules, 2009
Phthalimide reacted with phenacyl bromide under microwave irradiation to yield phenacyl isoindolidene-1,3-dione (3b), while 3a reacted with phenylhydrazine to yield the phenylhydrazone 4 that was readily converted into indoylphthalimide 8.
Morsy Ahmed El-Apasery   +1 more
doaj   +2 more sources

Chemiluminescence of phthalhydrazide derivatives in organized media: Interactions with surfactants and cyclodextrins

open access: yesJournal of Luminescence, 2011
The chemiluminescent oxidation of some phthalhydrazide derivatives, luminol (LUM), isoluminol (ISOL), N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and N-(6-aminohexyl)-N-ethylisoluminol (AHEI), has be ...
Raquel Maeztu   +3 more
openaire   +2 more sources

Montmorillonite K-10 Supported 11-molybdo-1-vanadophosphoric Acid (H4PMo11V1O40/K-10) Catalysts for Environmentally Benign Synthesis of 2H-indazolo[2,1-b]phthalazine-triones Under Solvent-free Condition [PDF]

open access: yesOrbital: The Electronic Journal of Chemistry, 2017
A series of 11-molybdo-1-vanadophosphoric acid supported on montmorillonite K-10 catalysts were prepared and characterized by FT-IR spectroscopy, thermal analysis, XRD, BET and SEM analysis techniques.
Laxmikant D. Chavan   +3 more
doaj   +4 more sources

Phthalhydrazide Chemiluminescence Method for Determination of Hydroxyl Radical Production: Modifications and Adaptations for Use in Natural Systems

open access: yesAnalytical Chemistry, 2010
The hydroxyl radical is formed through a variety of processes pertinent to natural and anthropogenic systems. Here we report development of a simple and sensitive trap-and-trigger chemiluminescence method based upon the hydroxylation of phthalhydrazide to 5-hydroxy-2,3-dihydro-1,4-phthalazinedione, which emits chemiluminescence when oxidized under ...
Miller, Christopher J   +2 more
openaire   +4 more sources

Cyclization of N-cinnamoyl phthalhydrazide

open access: yesTetrahedron Letters, 1977
J.-P. Anselme
openaire   +2 more sources

Practical and Scalable Manufacturing Process for the Key Intermediate of Poly(ADP-Ribose) Polymerase Inhibitor Olaparib. [PDF]

open access: yesACS Omega, 2022
Olaparib (Lynparza) is a potent, highly selective inhibitor of poly­(ADP-ribose)­polymerase enzymes, approved by the U.S. FDA and EMA for the treatment of ovarian cancer.
Chen Z   +7 more
europepmc   +2 more sources

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