Results 11 to 20 of about 326 (161)
One-pot and facile synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones using nano-NiO under solvent-free conditions [PDF]
In this article, nano-NiO as a heterogenuos and recyclable catalyst has been used for the synthesis of 1H-Pyrazolo[1,2-b]Phthalazine-5,10-Diones by the reaction of malononitrile, aldehydes and phthalhydrazide under solvent-free conditions. Short reaction
بهروز ملکی +3 more
doaj +2 more sources
Alum promoted synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives in water
A new and efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes using alum [KAl(SO4)2.12H2O] as catalyst was ...
Balaji Rajendra Madje +3 more
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Recruitment of macrophages and bone marrow stem cells to regenerating liver promoted by sodium phthalhydrazide in mice [PDF]
Pharmacological interventions which could be hepatoprotective, depending on bioavailability, anti-inflammatory and macrophage-targeting potential of drugs, are still at early preclinical stages. Existing evidence from many animal models of liver injury, as well as from human data, indicate that pharmacological and/or phytochemical interventions have ...
Danilova, I. G. +5 more
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Abstract Phthalhydrazide libraries are synthesized in solution from substituted hydrazines and phthalimides in several different library formats including single compounds, indexed sub-libraries and a full library. When carried out during solid-phase synthesis, this combinatorial cleavage and deprotection scheme offers the possibility for generating ...
Nielsen, John, Rasmussen, P. H.
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Phthalimide reacted with phenacyl bromide under microwave irradiation to yield phenacyl isoindolidene-1,3-dione (3b), while 3a reacted with phenylhydrazine to yield the phenylhydrazone 4 that was readily converted into indoylphthalimide 8.
Morsy Ahmed El-Apasery +1 more
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The chemiluminescent oxidation of some phthalhydrazide derivatives, luminol (LUM), isoluminol (ISOL), N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and N-(6-aminohexyl)-N-ethylisoluminol (AHEI), has be ...
Raquel Maeztu +3 more
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Montmorillonite K-10 Supported 11-molybdo-1-vanadophosphoric Acid (H4PMo11V1O40/K-10) Catalysts for Environmentally Benign Synthesis of 2H-indazolo[2,1-b]phthalazine-triones Under Solvent-free Condition [PDF]
A series of 11-molybdo-1-vanadophosphoric acid supported on montmorillonite K-10 catalysts were prepared and characterized by FT-IR spectroscopy, thermal analysis, XRD, BET and SEM analysis techniques.
Laxmikant D. Chavan +3 more
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The hydroxyl radical is formed through a variety of processes pertinent to natural and anthropogenic systems. Here we report development of a simple and sensitive trap-and-trigger chemiluminescence method based upon the hydroxylation of phthalhydrazide to 5-hydroxy-2,3-dihydro-1,4-phthalazinedione, which emits chemiluminescence when oxidized under ...
Miller, Christopher J +2 more
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Cyclization of N-cinnamoyl phthalhydrazide
J.-P. Anselme
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Practical and Scalable Manufacturing Process for the Key Intermediate of Poly(ADP-Ribose) Polymerase Inhibitor Olaparib. [PDF]
Olaparib (Lynparza) is a potent, highly selective inhibitor of poly(ADP-ribose)polymerase enzymes, approved by the U.S. FDA and EMA for the treatment of ovarian cancer.
Chen Z +7 more
europepmc +2 more sources

