Results 1 to 10 of about 3,118 (123)

Phylodynamic and Recombination Analyses of Avian Infectious Bronchitis GI-23 Reveal a Widespread Recombinant Cluster and New Among-Countries Linkages

Animals, 2021
Infectious bronchitis virus GI-23 lineage, although described approximately two decades ago in the Middle East, has recently drawn remarkable attention and is considered an “emerging” lineage due to its current spread to several other regions, including ...
Claudia Maria Tucciarone, Ahmed Ali, M H Houta   +2 more
exaly   +3 more sources

Phylodynamic analysis in the understanding of the current COVID-19 pandemic and its utility in vaccine and antiviral design and assessment

Human Vaccines and Immunotherapeutics, 2021
Over the last decades, the use of phylogenetic methods in the study of emerging infectious diseases has gained considerable traction in public health. Particularly, the integration of phylogenetic analyses with the understanding of the pathogen dynamics ...
Rodríguez-Morales Aj, Erika Vanessa Jiménez Posada, Diana Marcela Rojas Gallardo   +2 more
exaly   +2 more sources

Assessing the inference of single-cell phylogenies and population dynamics from CRISPR lineage recordings. [PDF]

PLoS Computational Biology
Multicellular organisms develop from a single cell by repeated rounds of cell division, differentiation, and death, which can be represented as a single-cell phylogenetic tree. Genetic lineage tracing allows us to investigate this development by tracking
Julia Pilarski, Tanja Stadler, Sophie Seidel   +2 more
doaj   +2 more sources

Molecular Surveillance and Evolutionary Dynamics of Porcine Circovirus Types 2 and 3 in China, 2022-2025. [PDF]

Transbound Emerg Dis
Porcine circovirus types 2 (PCV2) and 3 (PCV3) are globally distributed pathogens associated with reproductive disorders, subclinical infections, and multifactorial disease complexes in swine. To elucidate their epidemiological and evolutionary patterns in China, we examined 8426 clinical samples collected from 28 provincial‐level regions between 2022 ...
Chen Y, Lu Y, Zeng Y, Hu Y, Dong L, Lei M, Li P, Yan W, Jongkaewwattana A, Li W, Yu X, He Q.   +11 more
europepmc   +2 more sources

Phylodynamic Analysis and Implication of HCV Genotype 4 Variability on Antiviral Drug Response and T-Cell Recognition

Viruses, 2020
Therapies for HCV care could change the prevalence and the geographic distribution of genotypes due to differences in Sustained Virologic Response (SVR).
Vito Di Marco, Giuseppina Maria Elena Colomba, Donatella Ferraro   +2 more
exaly   +3 more sources

Integrated Genomic and Epidemiological Surveillance to Monitor SARS-CoV-2 Variants in Italy: Insights From the JN.1 Case Study (2023-2024). [PDF]

J Med Virol
ABSTRACT The epidemiology of SARS‐CoV‐2 is marked by the continuous emergence of new lineages. Early detection and assessment of their transmissibility can be challenging for surveillance systems that rely solely on case time series data. Genomic surveillance, focusing on identifying and characterizing circulating variants, can provide early insights ...
Manica M, Giombini E, Del Manso M, Molina Grané C, Ambrosio L, Bella A, di Martino A, Petrone D, Riccardo F, Poletti P, Pezzotti P, Palamara AT, Merler S, Stefanelli P.   +13 more
europepmc   +2 more sources

Phylogenetic and phylodynamic analyses of subtype-B metapneumovirus from chickens in Tunisia

Poultry Science, 2023
: Swollen Head Syndrome (SHS) is an economically important viral disease of chickens caused by avian metapneumovirus (aMPV). The virus comprises 6 different subtypes (A,B,C,D, New-1 and New-2). To date, no information was available on the presence of the
Jihène Lachheb, Abdeljelil Ghram, Imen Larbi   +2 more
exaly   +3 more sources

Unraveling the Transmission Dynamics of a Novel Norovirus GII.17[P17] Lineage During Two Consecutive Outbreaks in a Spanish Hospital. [PDF]

J Med Virol
ABSTRACT Norovirus outbreaks in healthcare settings pose significant challenges to infection prevention and control (IPC). To prevent and control such outbreaks efficiently, identifying sources and transmission clusters (TCs) is crucial but often limited by traditional outbreak investigations.
Kutter JS, Cuevas-Lobato O, Fernandez-Pacheco-Gonzalez-Echavarri BE, Moreno-Gomila C, Garcia-Ibañez N, Camacho J, Ruiz-Pedro E, Cabrerizo M, Alós JI, Diez-Fuertes F, Fernandez-Garcia MD.   +10 more
europepmc   +2 more sources

Whole-Genome Phylodynamic Analysis of Respiratory Syncytial Virus—Maryland, USA, 2018–2024 [PDF]

Viruses
Respiratory syncytial virus (RSV) is a leading cause of respiratory infections in infants and older adults, with epidemiological patterns shaped by viral evolution and diversity. To investigate the molecular epidemiology of RSV before and after the COVID-
Ting-Xuan Zhuang, Amary Fall, Julie M. Norton, Omar Abdullah, Andrew Pekosz, Eili Klein, Heba H. Mostafa   +6 more
doaj   +2 more sources

Host Species Contribution to the Spatiotemporal Dynamics of the 2024-2025 H5N1 Epidemic in Italy. [PDF]

Influenza Other Respir Viruses
ABSTRACT This study uses a phylodynamic approach to investigate host species contribution in the spatiotemporal dynamics of the highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b identified during the 2024–2025 epidemic in Italy.
Savegnago E, Cavicchio L, Dianati M, Salomoni A, Zecchin B, Sartori A, Giussani E, Moreno A, Zamperin G, Palumbo E, Schivo A, Salviato A, Ormelli S, Varotto M, Terregino C, Monne I, Fusaro A.   +16 more
europepmc   +2 more sources