Results 71 to 80 of about 1,369,061 (328)

Analysis and Comparison of Biochemical and Molecular Structural Characteristics and Phylogenetic Trend of Two h-TypeThioredoxin Isoforms from Grape (Vitis vinifera L. cv. Askari) [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2010
Thioredoxins (Trxs) are small heat-stable proteins that participate in dithiol-disulfide exchange reactions. In contrast to other organisms, plants contain six different Trx types: f, m, x, y, o and h.
reza Heydari   +2 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

DNA Barcode of Seven Indonesian Hornbills Species (Aves: Bucerotidae) Based on Mitochondrial DNA Cytochrome Oxidase Subunit I

open access: yesHayati Journal of Biosciences, 2018
DNA barcoding based on mitochondrial DNA COI gene is very useful in identifying of Indonesian hornbill. We sequenced the DNA barcode of seven hornbill species using the mitochondrial DNA COI gene to explore their genetic variation, identity, distance ...
Jarulis Jarulis   +3 more
doaj   +1 more source

Sequence comparison of the mitochondrial genomes of five brackish water species of the family Neritidae: Phylogenetic implications and divergence time estimation

open access: yesEcology and Evolution, 2022
Neritids are ancient gastropod species which can live in marine, brackish water, and freshwater environments. In this study, we sequenced and annotated the mitochondrial genomes of five brackish water neritids (i.e., Clithon corona, Clithon lentiginosum,
Jing Miao   +8 more
doaj   +1 more source

RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models

open access: yesBioinform., 2006
UNLABELLED RAxML-VI-HPC (randomized axelerated maximum likelihood for high performance computing) is a sequential and parallel program for inference of large phylogenies with maximum likelihood (ML).
A. Stamatakis
semanticscholar   +1 more source

Uprooted Phylogenetic Networks [PDF]

open access: yesBulletin of Mathematical Biology, 2017
The need for structures capable of accommodating complex evolutionary signals such as those found in, for example, wheat has fueled research into phylogenetic networks. Such structures generalize the standard model of a phylogenetic tree by also allowing for cycles and have been introduced in rooted and unrooted form.
P. Gambette, K. T. Huber, G. E. Scholz
openaire   +6 more sources

Assumption 0 analysis: comparative phylogenetic studies in the age of complexity [PDF]

open access: yes, 2008
Darwin's panoramic view of biology encompassed two metaphors: the phylogenetic tree, pointing to relatively linear (and divergent) complexity, and the tangled bank, pointing to reticulated (and convergent) complexity.
Brooks, D.R., Veller, M.G.P., van
core   +2 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Application of phylogenetic networks in evolutionary studies.

open access: yesMolecular biology and evolution, 2006
The evolutionary history of a set of taxa is usually represented by a phylogenetic tree, and this model has greatly facilitated the discussion and testing of hypotheses.
D. Huson, D. Bryant
semanticscholar   +1 more source

Phylogenetics of Allopolyploids [PDF]

open access: yesAnnual Review of Ecology, Evolution, and Systematics, 2017
We give an overview of recently developed methods to reconstruct phylog-enies of taxa that include allopolyploids that have originated in relatively recent times—in other words, taxa for which at least some of the parental lineages of lower ploidy levels are not extinct and for which ploidy information is clearly shown by variation in chromosome counts.
Oxelman, Bengt   +5 more
openaire   +4 more sources

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