Results 71 to 80 of about 455,803 (329)
Uprooted Phylogenetic Networks [PDF]
Bulletin of Mathematical Biology, 2017 The need for structures capable of accommodating complex evolutionary signals such as those found in, for example, wheat has fueled research into phylogenetic networks. Such structures generalize the standard model of a phylogenetic tree by also allowing for cycles and have been introduced in rooted and unrooted form.
P. Gambette, K. T. Huber, G. E. Scholz
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Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Phylogenetic Insights on Patterns of HIV-1 Spread and the Design of Epidemic Control Measures
Viruses, 2022 Phylogenetics provides a unique structural framework to track the spread of viral diseases, such as HIV-1 (human immunodeficiency virus type 1), the causative agent of AIDS (acquired immunodeficiency syndrome) [...]
Bluma G. Brenner
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Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
BMC Ecology and EvolutionBackground The evolution of differences in gamete size and number between sexes is a cornerstone of sexual selection theories. The green macroalga Ulva, with incipient anisogamy and parthenogenetic gametes, provides a unique system to investigate ...
Xiaojie Liu +6 more
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The dawn of relaxed phylogenetics.
PLoS Biology, 2023 Tracing the history of evolution across time is a primary goal of evolutionary biology. The 2006 publication of a landmark study on relaxed phylogenetics in PLOS Biology enabled biologists to shed light on evolution's tempo and shaped the future of ...
Jacob L Steenwyk, Antonis Rokas
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Molecular Phylogenetics and Mitochondrial Evolution
Life, 2021 The myth of a “typical” mitochondrial genome (mtDNA) is a rock-hard belief in the field of genetics, at least for the animal kingdom [...]
Andrea Luchetti, Federico Plazzi
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Phylogenetics of Allopolyploids [PDF]
Annual Review of Ecology, Evolution, and Systematics, 2017 We give an overview of recently developed methods to reconstruct phylog-enies of taxa that include allopolyploids that have originated in relatively recent times—in other words, taxa for which at least some of the parental lineages of lower ploidy levels are not extinct and for which ploidy information is clearly shown by variation in chromosome counts.
Oxelman, Bengt +5 more
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Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
FEBS Open Bio, EarlyView.With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet +6 more
wiley +1 more source
Ecological Indicators, 2023 Species in transitional areas often display adaptive responses to climate change and such areas may be crucial for long-term biodiversity conservation.
Run Zhou +10 more
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