Results 151 to 160 of about 629,067 (399)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

The complete mitochondrial genome of the deep-sea paskentanid snail Alviniconcha marisindica (Caenogastropoda: abyssochrysoidea) from the Carlsberg Ridge

open access: yesMitochondrial DNA. Part B. Resources
Alviniconcha marisindica Okutani 2014 is a deep-sea gastropod inhabited in hydrothermal vents of the Indo-Pacific. It belongs to superfamily Abyssochrysoidea. In the present study, we report the complete mitochondrial genome of A.
Mei Yang   +4 more
doaj   +1 more source

The study of the umbilical system in planktonic foraminifera in relation with depth of the Ziarat-kola section at the Maastrichtian, Central Alborz, IRAN [PDF]

open access: yes, 2009
The main aim of this research is study of the planktonic foraminifera morphogroups distinction genus to perform by changing the umbilicus area in Ziarat-kola section to find novel results.
Behnaz Balmaki   +2 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Introduction of Fusarium sp. UTMC 5039 as a potent fungal strain for biosurfactant production and evaluation of its potential for crude oil bioremediation [PDF]

open access: yesBiological Journal of Microorganism, 2017
Introduction: Biosurfactants are biological surface active agents which are used in many applications such as oil bioremediation of contaminated soils.
Hamid Moghimi   +4 more
doaj  

Temporal Phylogenetic Networks and Logic Programming

open access: yes, 2005
The concept of a temporal phylogenetic network is a mathematical model of evolution of a family of natural languages. It takes into account the fact that languages can trade their characteristics with each other when linguistic communities are in contact,
Erdem, Esra   +2 more
core   +1 more source

A molecular phylogenetic study of Deschampsia (Poaceae: Aveneae) inferred from nuclear ITS and plastid trnL sequence data: support for the recognition of Avenella and Vahlodea [PDF]

open access: yes, 2007
The circumscription and phylogeny of Deschampsia were studied for the first time by parsimony analysis of nuclear ribosomal internal transcribed spacer (ITS) and plastid trnL intron sequences.
Chiapella, Jorge Oscar
core  

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

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