Results 121 to 130 of about 8,200,222 (305)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
N-Heterocyclic carbene-catalyzed activation of esters for asymmetric reactions
, 2013 The work incorporated in this Ph.D. thesis was performed in the division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, under the supervision of Professor Yonggui Robin Chi. My study
Hao, Lin
core
Evolution of physico-chemical properties of Dicranopteris linearis-derived activated carbon under various physical activation atmospheres. [PDF]
Sci Rep, 2021 Mai NT +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
[Sport and physical activity].
La Pediatria medica e chirurgica : Medical and surgical pediatrics, 2010 A regular sport activity involves physical and psychological benefits helping to improve the quality of life at any age. This aspect is even more important in the developing age, when the sport takes on a role of training and education. In this context, instances directed to allow adolescent and young adults with heart disease to practice sports seem ...
Bria, Serena, Zeppilli, Paolo
openaire +2 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Enhanced Desilication of High Alumina Fly Ash by Combining Physical and Chemical Activation
, 2019 In this work, a physical–chemical activation desilication process was proposed to extract silica from high alumina fly ash (HAFA). The effects of fly ash size, hydrochloric acid concentration, acid activation time, and reaction temperature on the ...
Shu-Ying Sun +4 more
core +1 more source
A review on activation methods of date seeds for removal of pollutants from water
Discover Applied SciencesThere has been an increase in nitrate levels in water bodies, posing a significant environmental and public health problem due to runoff from agriculture and the discharge of industrial effluents.
P. Jagadesh +4 more
doaj +1 more source
Adult ADHD: Influence of Physical Activation, Stimulation, and Reward on Cognitive Performance and Symptoms. [PDF]
J Atten Disord, 2021 Kallweit C +3 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source