Results 71 to 80 of about 8,200,222 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assisted Oocyte Activation Method (Ca ACTIVATION) Improves Fertilization in Patients with Recurrent Fertilization Failure

open access: yes, 2022
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad   +2 more
core   +1 more source

Physical activity promotion [PDF]

open access: yesBritish Journal of General Practice, 2010
Davies and Garbutt wrote an important and commendable editorial on exercise prescription;1 however, there are some fundamental issues raised requiring clarification and further consideration. First, when measured objectively, a staggering 95% of the adult population (UK and US) do not meet the minimum recommended levels of physical activity to confer ...
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Preparation of Activated Carbon from Oil Sands Coke by Chemical and Physical Activation Techniques [PDF]

open access: yes, 2012
Oil sands coke is a by-product resulting from the upgrading of heavy crude bitumen to light synthetic oil. This research investigates the preparation of activated carbon from oil sands cokes by using both chemical activation and physical activation ...
Morshed, Golam
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Physical mechanisms relevant to flow resistance in textured microchannels [PDF]

open access: yes, 2017
Flow resistance of liquids flowing through microchannels can be reduced by replacing flat, no-slip boundaries with boundaries adjacent to longitudinal grooves containing an inert gas, resulting in apparent slip.
M. Hodes   +7 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Physical and Chemical Activation of Graphene-Derived Porous Nanomaterials for Post-Combustion Carbon Dioxide Capture

open access: yes, 2021
Activation is commonly used to improve the surface and porosity of different kinds of carbon nanomaterials: activated carbon, carbon nanotubes, graphene, and carbon black.
Firdaus, Rabita Mohd   +9 more
core   +1 more source

Synthesis of Physically Activated Carbons from Vitellaria paradoxa Shells for Supercapacitor Electrode Applications

open access: yesInorganics
This study investigates the processing of shea nut shells (SNSs), an abundant agricultural waste, into porous activated carbon for supercapacitor electrodes through a two-stage thermal treatment involving pyrolysis and physical activation with CO2 and ...
Joshua Atta Alabi   +8 more
doaj   +1 more source

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