Results 41 to 50 of about 6,017,492 (315)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

The effects of different doses of exercise on pancreatic β-cell function in patients with newly diagnosed type 2 diabetes: study protocol for and rationale behind the “DOSE-EX” multi-arm parallel-group randomised clinical trial

Trials, 2021
Background Lifestyle intervention, i.e. diet and physical activity, forms the basis for care of type 2 diabetes (T2D). The current physical activity recommendation for T2D is aerobic training for 150 min/week of moderate to vigorous intensity ...
Mark P. P. Lyngbaek, Grit E. Legaard, Sebastian L. Bennetsen, Camilla S. Feineis, Villads Rasmussen, Nana Moegelberg, Cecilie F. Brinkløv, Anette B. Nielsen, Katja S. Kofoed, Carsten A. Lauridsen, Caroline Ewertsen, Henrik E. Poulsen, Robin Christensen, Gerrit Van Hall, Kristian Karstoft, Thomas P. J. Solomon, Helga Ellingsgaard, Thomas P. Almdal, Bente K. Pedersen, Mathias Ried-Larsen   +19 more
doaj   +1 more source

Short, frequent high-intensity physical activity breaks reduce appetite compared to a continuous moderate-intensity exercise bout

Endocrine Connections, 2022
A single exercise session can affect appetite-regulating hormone s and suppress appetite. The effects of short, regular physical activity breaks across th e day on appetite are unclear.
Benjamin D Maylor, Julia K Zakrzewski-Fruer, Julia K Zakrzewski-Fruer, Daniel P Bailey   +3 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Short- and long-term effects of a multi-component physical activity intervention in primary school [PDF]

, 2012
There is compelling evidence that physical activity has numerous health benefits during childhood and adolescence. Insufficient levels of physical activity on the other hand can consequently affect cardiovascular and bone health, which may result in ...
Meyer, Ursina
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of lifestyle risk behaviour clustering on cardiovascular disease among UK adults: latent class analysis with distal outcomes

Scientific Reports, 2022
Lifestyle risk behaviours such as smoking, physical inactivity, and unhealthy diet account for a considerable disease burden globally. These risk behaviours tend to cluster within an individual, which could have detrimental health effects. In this study,
Teketo Kassaw Tegegne, Sheikh Mohammed Shariful Islam, Ralph Maddison   +2 more
doaj   +1 more source

Adolescent Physical Education and Physical Activity in California [PDF]

, 2011
Based on 2007 California Health Interview Survey data, examines participation in physical education and other physical activity among adolescents ages 12 to 17 by gender and county, and implications for health outcomes.
Allison L. Diamant, Joelle Wolstein, Susan H. Babey   +2 more
core  

Recall of physical activity advice was associated with higher levels of physical activity in colorectal cancer patients. [PDF]

, 2015
The present study tested the hypothesis that recall of receiving physical activity (PA) advice would be associated with higher levels of PA in patients with a diagnosis of colorectal cancer (CRC)
Beeken, R, Fisher, A, Wardle, J, Williams, K   +3 more
core   +1 more source