Results 51 to 60 of about 5,366,888 (247)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Relationship Of Physical Activity Levels With Genesis Obesity In Faculty Of Medicine University Of Riau Generation 2012 & 2013 [PDF]

, 2015
According to data from the Health Research (Riskesdas) Ministry ofHealth of the Republic of Indonesia in 2013, the prevalence of obese adolescentsaged over 18 years in the province of Riau based on measurements of body massindex (BMI) of 32%. This figure
Bebasari, E. (Eka), Ernalia, Y. (Yanti), Utami, T. W. (T)   +2 more
core  

Physical activity education in the undergraduate curricula of all UK medical schools: are tomorrow's doctors equipped to follow clinical guidelines? [PDF]

, 2012
Physical activity (PA) is a cornerstone of disease prevention and treatment. There is, however, a considerable disparity between public health policy, clinical guidelines and the delivery of physical activity promotion within the National Health Service ...
Chew, S, Coombs, N, Hamer, M, Stamatakis, E, Weiler, R   +4 more
core   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Creative dance for older adults: A new social prescription pathway?

This dataset includes qualitative data collected from two funded research projects: 1) The impact of a creative contemporary dance programme for older adults; 2) A creative contemporary dance programme for older adults: A new social prescription pathway?
Centre for Physical Activity and Life Sciences, Spencer, Melinda   +1 more
core   +2 more sources

Phases in Physical Activity Initiation and Maintenance Among Men with Serious Mental Illness [PDF]

, 2007
There is increasing interest in the role of physical activity in mental health promotion, and research suggests that regular participation can provide mental and physical health benefits.
Carless, D
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Increasing Physical Activity Through Recess [PDF]

, 2012
Summarizes research on the effects of recess, including its benefits as an effective and efficient way to increase the amount of physical activity and enhance academic performance and trends in daily recess by school location and student ...

core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Intense physical activity is associated with cognitive performance in the elderly [PDF]

, 2012
Numerous studies have reported positive impacts of physical activity on cognitive function. However, the majority of these studies have utilised physical activity questionnaires or surveys, thus results may have been influenced by reporting biases ...
AIBL research group,, Ames, D, Brown, B. M, Burnham, S, Ellis, K. A, Gupta, V. B, Martins, R. N, Masters, C. L, Mondal, A, Peiffer, J. J, Rainey-Smith, S. R, Rowe, C. C, Sohrabi, H. R, Szoeke, C, Taddei, K   +14 more
core   +3 more sources