Results 51 to 60 of about 6,017,492 (315)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Applying a technology‐based system for weight loss in adults with obesity

open access: yesObesity Science & Practice, 2016
Summary Objective The aim of this study was to compare an in‐person, group‐based behavioral weight loss intervention to technology‐based interventions in adults with obesity.
R. J. Rogers   +7 more
doaj   +1 more source

Special Article: Physical Activity, Physical Fitness, and Cardiovascular Risk Factors in Childhood [PDF]

open access: yes, 2007
In adults, physical activity and exercise training are associated with reduced cardiovascular morbidity and mortality, a reduced likelihood of developing adverse cardiovascular risk factors, and improved insulin sensitivity.
Becque MD   +6 more
core   +3 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Modifiable factors which predict children’s gross motor competence: a prospective cohort study

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2019
Background Fundamental motor skills (FMS) are important for physical activity and healthy weight status in children, yet it is unclear which early childhood factors facilitate subsequent motor skill.
Lisa M. Barnett   +3 more
doaj   +1 more source

A Quasi-Experimental Study of the Effects of an Outdoor Learning Program on Physical Activity Patterns of Children with a Migrant Background: the PASE Study

open access: yesPhysical Activity and Health, 2021
Introduction: Despite the recognized benefits of physical activity on health, most youth, especially those with a migrant background, do not meet movement guidelines. Outdoor learning is recognized as a promising intervention to address this issue.
Yannick Lacoste   +3 more
doaj   +1 more source

Increasing Physical Activity Through Recess [PDF]

open access: yes, 2012
Summarizes research on the effects of recess, including its benefits as an effective and efficient way to increase the amount of physical activity and enhance academic performance and trends in daily recess by school location and student ...

core  

Physical activity and quality of life of amputees in southern Brazil [PDF]

open access: yes, 2011
Physical activity is a positive component of human health. Its effects are associated with improvement in physical, psychological and social aspects of quality of life. Physical activity is therefore an important factor in the rehabilitation of amputees.
da Silva, Rudney   +4 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Regional variation in adipose tissue lipolysis in lean and obese men.

open access: yesJournal of Lipid Research, 1991
Biopsies of adipose tissue were obtained from two subcutaneous regions (abdominal and femoral) in a sample of 54 men (32 obese and 22 lean subjects).
P Mauriège   +6 more
doaj   +1 more source

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