Results 71 to 80 of about 6,932,206 (380)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Potensi Ekstrak Kulit Buah Manggis sebagai Inhibitor Korosi Baja Karbon dalam Larutan NaCl 1% Jenuh Karbon Dioksida

open access: yesΑl-Kimiya: Jurnal Ilmu Kimia dan Terapan, 2019
Pemanfaatan limbah bahan alam sebagai inhibitor korosi belum banyak dilaporkan. Diantaranya adalah kulit buah manggis (Garcinia mangostana L.) yang dalam bentuk ekstraknya mengandung senyawa golongan flavonoid, alkaloid, dan tanin.
Tety Sudiarti   +2 more
doaj   +1 more source

Quantum chemical exercise linking computational chemistry to general chemistry topics

open access: yesChemistry Teacher International, 2020
Students in a second semester general chemistry course used quantum chemical calculations to investigate and reinforce general chemistry concepts. Students explored the isomers of hypochlorous acid, made predictions of miscibility via dipole moments ...
Simpson Scott   +5 more
doaj   +1 more source

Reactive molecular dynamics simulations of organometallic compound W(CO)6 fragmentation

open access: yes, 2019
Irradiation- and collision-induced fragmentation studies provide information about geometry, electronic properties and interactions between structural units of various molecular systems. Such knowledge brings insights into irradiation-driven chemistry of
de Vera, Pablo   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Unified Scale of Natural Waters

open access: yesGeoresursy, 2018
The article presents a continual scale of natural waters based on the characteristics of a vector, constructed on the superimposed cationic and anionic Gibbs triangles.
V.F. Nikolaev   +5 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

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