Results 71 to 80 of about 1,890,297 (287)

Cavitation is the determining mechanism for the atomization of high-viscosity liquid

open access: yesiScience
Summary: Piezoelectric atomization is becoming mainstream in the field of inhalation therapy due to its significant advantages. With the rapid development of high-viscosity gene therapy drugs, the demand for piezoelectric atomization devices is ...
Zhenzhen Gui   +9 more
doaj   +1 more source

Modeling the Enceladus plume--plasma interaction

open access: yes, 2010
We investigate the chemical interaction between Saturn's corotating plasma and Enceladus' volcanic plumes. We evolve plasma as it passes through a prescribed H2O plume using a physical chemistry model adapted for water-group reactions.
Aikin   +26 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Synthesis and Structural and Electrochemical Characterization of Carbon Fiber/MnO2 Composites for Hydrogen Storage and Electrochemical Sensing

open access: yesFibers
Hydrogen, as an alternative energy carrier, presents significant prospects for the transition to more environmentally friendly energy solutions. However, its efficient and safe storage remains a challenge, as materials with high adsorbent capacity and ...
Loukia Plakia   +7 more
doaj   +1 more source

The cupric complexes of glycine and of alanine [PDF]

open access: yes, 1932
The following report is the first of a projected series of studies of the physical chemistry of the compounds of the heavy metals, particularly of copper and of iron, with substances of biological importance. These studies are invited by the accumulation
Borsook, Henry, Thimann, Kenneth V.
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Tracing the Physical Conditions in Active Galactic Nuclei with Time-Dependent Chemistry

open access: yes, 2013
We present an extension of the code ProDiMo that allows for a modeling of processes pertinent to active galactic nuclei and to an ambient chemistry that is time dependent. We present a proof-of-concept and focus on a few astrophysically relevant species,
Aresu, Giambattista   +5 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Tailoring the Electron Affinity of Au13 Superhalogen via Ligand Design

open access: yesAggregate
The thiolate (RS)‐protected neutral gold cluster Au25(SR)180, which has an icosahedral Au13 core, is regarded as a superhalogen due to its comparably high electron affinity (EA) to those of halogen atoms.
Shun Ito   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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