Results 41 to 50 of about 1,150,022 (269)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Multimodal neuroimaging insights into central mechanisms of overactive bladder with an empty bladder: a cross-sectional study

European Journal of Medical Research
Background and objective Overactive bladder (OAB) is a complex condition involving central nervous system (CNS) processes that are not fully understood.
Yangkun Feng, Yuwei Zhang, Ju Zhang, Yifan Sun, Deshui Yu, Huihui Song, Kaixin Zhang, Feng Lu, Xi Liu, Xiuhong Hua, Siyi Fu, Jia Xu, Yi Fan, Jianfeng Shao, Ye Hua   +14 more
doaj   +1 more source

Evolving multimorbidity patterns among ageing adults with cardiovascular disease continuum in Southwest China: A longitudinal cohort study

International Journal of Cardiology. Cardiovascular Risk and Prevention
Background: The progression of multimorbidity in Chinese ageing adults with cardiovascular diseases remains inadequately understood. This study investigates the longitudinal evolution of cardiovascular disease continuum (CVDC)-related multimorbidity ...
Xiaoya Qi, Ziyue Zhang, Meng Jia, Yangping Zhang, Shuang Feng, Ruixue Bai, Siyao Wang, Jinning Mao, Shu Su   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Physical Examination of the Hip

Sports Health: A Multidisciplinary Approach, 2020
The hip and pelvis have a complex anatomy and are a common source of pain and injury in the athletic population. The clinical examination of the hip requires a systematic approach to differentially diagnose hip problems with overlapping pain referral patterns.
Daniel, Wichman, Jonathan P, Rasio, Austin, Looney, Shane J, Nho   +3 more
openaire   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The relationship between perceived stress and job burnout of police officers during the COVID-19 pandemic: the mediating role of social support, sleep quality and resilience

BMC Public Health
Background With the rapid spread of Corona Virus Disease 2019 (COVID-19) in China, police officers were undergoing higher job stress, which made them physically and mentally exhausted, eventually leading to job burnout.
Xuyu Chen, Yi Xu, Qi Zhang, Hongwei Huang, Xiaodong Tan, Yang Yang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source