Results 51 to 60 of about 8,497,984 (308)
Journal of Ophthalmology, 2019 Background. In recent decades, the prevalence rate of myopia has markedly increased, especially among teenagers. Our purpose was to determine the incidence of myopia and identify the related risk factors among schoolchildren in the experimental classes ...
Lin-song Qi +6 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Application value of early lung cancer screening based on artificial intelligence
Journal of Radiation Research and Applied SciencesObjective: Lung cancer represents a predominant malignancy within the pulmonary system globally, necessitating enhanced screening strategies to improve patient prognosis. This study aims to assess the efficacy and significance of artificial intelligence (
Chunyan Cheng, Yuan Li, Feng Wu
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2023 Yimy F Medina,1,2,* Alvaro J Ruiz,1,* Martin A Rondon1 1PhD Program in Clinical Epidemiology, Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogotá, Colombia; 2Rheumatology Unit, Internal Medicine ...
Ruiz AJ, Rondon MA, Medina YF
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
BMC GastroenterologyBackground The factors influencing nonobese Metabolic dysfunction-associated steatotic liver disease are discussed, and an online dynamic nomogram model is constructed.
Tingting Zheng +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Frontiers in EndocrinologyObjectiveTo investigate the association between the triglyceride-glucose (TyG) index and hyperuricemia (HUA) in an apparently healthy population, specifically defined as individuals presenting with zero components of metabolic syndrome (MetS) components.
Xing Guan +6 more
doaj +1 more source