Results 61 to 70 of about 8,497,984 (308)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Role of Physical Examination in Patients with Obstructive Sleep Apne Syndrome

, 2019
Objectives:To correlate the physical examination findings, Epworth Sleepiness Scale (ESS) and apnea-hypopnea index (AHI) in patients investigated for obstructive sleep apnea syndrome (OSAS).Materials and Methods:Patients who are investigated with a ...
Süha Beton, Nurlan İsayev, Yücel Anadolu, Hazan Başak, Selçuk Mülazımoğlu   +4 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Health Assessment and Physical Examination

, 2013
"This first Australia and New Zealand edition of the comprehensive Estes’ Health Assessment and Physical Examination is designed to teach students to assess a patient’s physical, psychological, cultural and emotional dimensions of health as a foundation ...
Theobald, Karen A., Harvey, Theresa, Estes, Mary Ellen Zator, Calleja, Pauline   +3 more
core  

Detection Rate of Non-alcoholic Fatty Liver Disease and Its Influencing Factors: Analysis Based on the Data of 320 000 Beijing Population [PDF]

Zhongguo quanke yixue
Background Non-alcoholic fatty liver disease has showed a high prevalence and a increasing trend especially towards younger age. It is of great public health significance to reduce damage through early detection of NAFLD in physical examination and ...
DOU Ziyan, QIAN Wenhong, KONG Linrun, CHEN Ye, LI Mingliang, ZHANG Jingbo
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A new method for teaching physical examination to junior medical students

, 2016
Meelad Sayma, Hywel Rhys Williams Peninsula College of Medicine and Dentistry, Plymouth, UK Introduction: Teaching effective physical examination is a key component in the education of medical students.
Williams HR, Sayma M
core  

Multimodal neuroimaging insights into central mechanisms of overactive bladder with an empty bladder: a cross-sectional study

European Journal of Medical Research
Background and objective Overactive bladder (OAB) is a complex condition involving central nervous system (CNS) processes that are not fully understood.
Yangkun Feng, Yuwei Zhang, Ju Zhang, Yifan Sun, Deshui Yu, Huihui Song, Kaixin Zhang, Feng Lu, Xi Liu, Xiuhong Hua, Siyi Fu, Jia Xu, Yi Fan, Jianfeng Shao, Ye Hua   +14 more
doaj   +1 more source

Evolving multimorbidity patterns among ageing adults with cardiovascular disease continuum in Southwest China: A longitudinal cohort study

International Journal of Cardiology. Cardiovascular Risk and Prevention
Background: The progression of multimorbidity in Chinese ageing adults with cardiovascular diseases remains inadequately understood. This study investigates the longitudinal evolution of cardiovascular disease continuum (CVDC)-related multimorbidity ...
Xiaoya Qi, Ziyue Zhang, Meng Jia, Yangping Zhang, Shuang Feng, Ruixue Bai, Siyao Wang, Jinning Mao, Shu Su   +8 more
doaj   +1 more source