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The genetics of physical fitness [PDF]

open access: yesBritish Journal of Sports Medicine, 2000
Editor,—Any paragraph that starts with the statement “We must be cautious, however, that such research is not misused.”1 is obviously completely ignoring the history of science in general and sport in particular. From the post hoc hand wringing of the Manhattan project scientists to the current debate about “genetically modified organisms”, it is ...
David R. Woods, Hugh Montgomery
openaire   +6 more sources

Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish

open access: yesExperimental Gerontology, 2023
Sarcopenia is a common skeletal muscle degenerative disease characterized by decreased skeletal muscle mass and mitochondrial dysfunction that involves microRNAs (miR) as regulatory factors in various pathways.
Zhang-Lin Chen   +13 more
doaj   +1 more source

Exercise Training Upregulates Cardiac mtp Expression in Drosophila melanogaster with HFD to Improve Cardiac Dysfunction and Abnormal Lipid Metabolism

open access: yesBiology, 2022
Current evidence suggests that the heart plays an important role in regulating systemic lipid homeostasis, and high-fat diet (HFD)-induced obesity is a major cause of cardiovascular disease, although little is known about the specific mechanisms involved.
Tianhang Peng   +6 more
doaj   +1 more source

Metabolic Flexibility and Mechanical Efficiency in Women Over-60

open access: yesFrontiers in Physiology, 2022
Purpose: Aging deteriorates metabolic flexibility (MF). Moreover, recent studies show that glycolysis is barely increased despite impoverished lipid metabolism, in addition to increased relevance of muscle power in older adults.
Cristina Blasco-Lafarga   +5 more
doaj   +1 more source

Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish

open access: yesBiology, 2021
Long-term imbalance between fatigue and recovery may eventually lead to muscle weakness or even atrophy. We previously reported that excessive exercise induces pathological cardiac hypertrophy.
Chen-Chen Sun   +7 more
doaj   +1 more source

Treadmill exercise prevents the hyperexcitability of pyramidal neurons in medial entorhinal cortex in the 3xTg-AD mouse model of Alzheimer's disease

open access: yesExperimental Gerontology, 2023
Neuronal hyperactivity is a key abnormality in early stage Alzheimer's disease (AD). Medial entorhinal cortex (mEC) plays a vital role in memory function and is affected early in AD.
Huimin Chen   +5 more
doaj   +1 more source

Alcohol Induces Zebrafish Skeletal Muscle Atrophy through HMGB1/TLR4/NF-κB Signaling

open access: yesLife, 2022
Excessive alcohol consumption can cause alcoholic myopathy, but the molecular mechanism is still unclear. In this study, zebrafish were exposed to 0.5% alcohol for eight weeks to investigate the effect of alcohol on skeletal muscle and its molecular ...
Wei Wen   +6 more
doaj   +1 more source

Changes in Plantar Pressure Levels Generated Using Military Backpack During Standing Position: An Experimental Study

open access: yesRevista de Educação Física, 2021
Introduction: The feet are one the main anatomical site affected by injuries arising from load carriage tasks and can negatively affect the soldier mobility reducing the operational capability of an entire military troops.
Fabio Alves Machado Gomes   +5 more
doaj   +1 more source

Descended Social Anxiety Disorder and Craving in Women Heroin Dependence Through Exercise Alerts Plasma Oxytocin Levels

open access: yesFrontiers in Psychiatry, 2021
Purpose: This study explored the association between peripheral blood oxytocin (OT) and social anxiety disorder (SAD) and cue-induced cravings in female heroin addicts. The effect of exercise on alleviation of SAD and OT levels was also explored.Methods:
Jing Song Wang   +8 more
doaj   +1 more source

Changes in Physical Status of Young Women in Response to Exercise Training [PDF]

open access: yesSport Mont, 2021
Fitness-related benefits result in essential changes in physical fitness level in young women. This study was conducted with fitness centre clients (35 women with an average age of 26.4±2.2 years).
Olena Andrieieva   +8 more
doaj   +1 more source

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