Results 41 to 50 of about 295,009 (312)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

National physical education curriculum: motor and cardiovascular health related fitness in Greek adolescents. [PDF]

, 2007
Background: State school physical education (PE) programmes are common throughout Greece. However, it is not known if the main objectives of the Greek PE curriculum are achieved.
Bouziotas, Constantin, Koutedakis, Yiannis   +1 more
core  

Quality of life is associated with physical activity and fitness in cystic fibrosis [PDF]

, 2014
BACKGROUND: Health-related and disease-specific quality of life (HRQoL) has been increasingly valued as relevant clinical parameter in cystic fibrosis (CF) clinical care and clinical trials.
Helge Hebestreit, Schmid, K, Junge, Sibylle, Hebestreit, Helge Uwe, Hebestreit, H, Schindler, C, Schmid, Kerstin, Kriemler, Susi, Christian Schindler, Schenk, T, Hebestreit, Alexandra, Ballmann, Manfred, Hebestreit, A, Kerstin Schmid, Stephanie Kieser, Hans-Georg Posselt, Manfred Ballmann, Thomas Schenk, Roth, K, Schenk, Thomas, Junge, S, Posselt, H G, Posselt, Hans-Georg, Sibylle Junge, Alexandra Hebestreit, Kieser, Stephanie, Hebestreit, Helge, Ballmann, M, Susi Kriemler, Schindler, Christian, Roth, Kristina, Kristina Roth   +31 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Physical Activity & Sport in the Lives of Girls: Physical & Mental Health Dimensions from an Interdisciplinary Approach [PDF]

, 1997
The report compiles research information from the disciplines of psychology, sociology, and physiology. Emphasizing the importance of sport for growing girls, the report cites several studies demonstrating that girls' participation in sport enhances body
President's Council on Physical Fitness and Sport
core  

Effects of priming exercise on oxygen uptake kinetics, muscle oxygenation, and metabolic load in trained anaerobic athletes: a randomized crossover trial [PDF]

PeerJ
Background This study aimed to compare the acute and residual physiological responses elicited by three different priming exercise strategies, including high-intensity priming exercise (HIPE), low-intensity priming exercise (LIPE), and low-intensity ...
Jing Qing, Yingying Hou, Hanyue Zhang, Tingting Sun, Xiao Jia, Zhenxing Kong   +5 more
doaj   +2 more sources

Plasma BDNF and TrkB mRNA in PBMCs Are Correlated With Anti-depressive Effects of 12-Weeks Supervised Exercise During Protracted Methamphetamine Abstinence

Frontiers in Molecular Neuroscience, 2020
Purpose: The aim of this study was to evaluate the potential neurotrophic factors and expression of neurotrophin receptors in peripheral blood mononuclear cells linked with the antidepressant action of exercise intervention during protracted ...
Jue Yang, Jue Yang, Jun Tan, Lan Zheng, Chun Xia Lu, Wen Qi Hou, Yi Liu, Qiu Fang Li, Jin Xiu Li, Dan Cheng, Xu Luo, Jun Zhang   +11 more
doaj   +1 more source

Physical Fitness of Physical Therapy Students

Physical Therapy, 1983
Physical fitness norms do not exist for physical therapists or physical therapy students. This lack, in part, reflects the complexity of physical fitness and the scarcity of data reported on physical fitness norms of other populations. This report describes the methods used and the results obtained for 16 physical fitness factors of 98 female and 13 ...
Sobush, Dennis, Fehring, Richard
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Current status and related factors of breakfast skipping among adolescents aged 12–15 years in Shandong Province, China: a cross-sectional study

BMC Public Health
Background Regular breakfast consumption is essential for adolescent health, providing critical nutrients for growth, development, and cognitive performance. However, breakfast skipping remains prevalent among adolescents globally and has been associated
Zhihao Huang, Qing Zhang, Chunyang Li, Hanhui Liu, Kunzong Tian   +4 more
doaj   +1 more source