Results 71 to 80 of about 5,609,700 (305)

Genetic mechanisms, brain structures, and peripheral biomarkers mediate the relationship between physical frailty and neuropsychiatric disorders

Journal of Advanced Research
Introduction: Physical frailty, which is characterized by multisystem functional decline, has emerged as a significant risk factor for adverse health outcomes.
Pei-Yang Gao, Yan Fu, Xiao-Yu He, Dan-Dan Zhang, Hao-Chen Chi, Yi-Ming Huang, Zhi-Bo Wang, Wei Zhang, Ya-Nan Ou, Yi-Jun Ge, Jia You, Ling-Zhi Ma, Yi-Xuan Qiang, Bing Zhao, Hai-Hong Yu, Jianfeng Feng, Lan Tan, Wei Cheng, Ya-Ru Zhang, Jin-Tai Yu   +19 more
doaj   +1 more source

Diagnostic accuracy of the short physical performance battery for detecting frailty in older people

, 2020
The Short Physical Performance Battery (SPPB) is widely used to predict negative health-related outcomes in older adults. However, the cutoff point for the detection of the frailty syndrome is not yet conclusive.
Mello, Mateus, Mateus Mello, Lygia Paccini Lustosa, Tereza Loffredo Bilton, Alexandre, Tiago da Silva, Monica Rodrigues Perracini, Tiago da Silva Alexandre, Roberta de Oliveira Máximo, Bilton, Tereza L, Eduardo Ferriolli, Máximo, Roberta de Oliveira, Ferriolli, Eduardo, Perracini, Monica R, Lustosa, Lygia P   +13 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Multidimensional and Physical Frailty in Elderly People: Participation in Senior Organizations Does Not Prevent Social Frailty and Most Prevalent Psychological Deficits

Frontiers in Public Health, 2020
Purpose: The study explores how the involvement in community-based senior organizations affects the prevalence of multidimensional and physical frailty among community dwelling elderly people.Materials and Methods: The group of 1,024 elderly people (270 ...
Magdalena Sacha, Jerzy Sacha, Jerzy Sacha, Katarzyna Wieczorowska-Tobis   +3 more
doaj   +1 more source

Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study investigated the association between frailty and cancer incidence and mortality in patients with rheumatoid arthritis (RA). It aimed to identify how frailty influences cancer risk and cancer‐specific outcomes. Methods This retrospective cohort study analyzed data from the Veterans’ Affairs Rheumatoid Arthritis Registry (2002–2023).
Bhavik Bansal, Aaron Baraff, Katherine Wysham, James S. Andrews, Bryant R. England, Ted R. Mikuls, Joshua Baker, Kaleb Michaud, Alexa Meara, Una Makris, Carolyn Presley, Ariela Orkaby, Namrata Singh   +12 more
wiley   +1 more source

Simultaneous Employment of the FRAIL Scale and the Tilburg Frailty Indicator May Identify Elderly People Who Require Different Interventional Strategies

Clinical Interventions in Aging, 2020
Magdalena Sacha,1 Jerzy Sacha,2,3 Katarzyna Wieczorowska-Tobis1 1Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland; 2Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland ...
Sacha M, Sacha J, Wieczorowska-Tobis K
doaj  

Parametric frailty and shared frailty survival models [PDF]

Frailty models are the survival data analog to regression models, which account for heterogeneity and random effects. A frailty is a latent multiplicative effect on the hazard function and is assumed to have unit mean and variance theta, which is ...
Roberto G. Gutierrez
core  

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

Arthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar, Joshua Baker, Katherine D Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Frailty in ethnic minority women

, 2021
In majority populations in high- and middle-income countries, women live longer yet experience higher levels of frailty than men of the same age. It is unclear whether this ‘sex–frailty paradox’ is present in ethnic minority populations.
Weerasekera, S, Reid, N, Gordon, EH, Hubbard, RE   +3 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source