Results 91 to 100 of about 5,609,700 (305)

Defining Biomarkers of Frailty in the Kidney: Implications for Endobiotic and Xenobiotic Metabolism in Mice

open access: yes, 2023
Frailty describes individuals with increased susceptibility to adverse health outcomes. The frailty index (FI) quantifies frailty by measuring deficit accumulation. This project aimed to characterize the molecular signature of frailty in the mouse kidney
Hodgins, Maddison
core  

Midlife Life’s Simple 7, Psychosocial Health, and Physical Frailty, Hospital Frailty, and Comprehensive Frailty 10 Years Later

open access: yes, 2023
This study aims to examine the associations between midlife Life’s Simple 7 (LS7) status, psychosocial health (social isolation and loneliness), and late-life multidimensional frailty indicators, and to investigate their synergistic effect on ...
Chunmiao Zhou   +8 more
core   +1 more source

Ultra‐White Elastomeric Coatings for Daytime Radiative Cooling

open access: yesAdvanced Materials Technologies, EarlyView.
Passive daytime radiative cooling meets elasticity in a new class of ultra‐white silicone coatings. Combining high solar reflectance with strong sky‐window emission, they hold surfaces below ambient temperature under full sunlight while remaining flexible and stretchable. This combination of cooling performance and mechanical flexibility enables energy‐
Abdulrahman Aljwirah   +5 more
wiley   +1 more source

Proportional hazards models with discrete frailty

open access: yes
We extend proportional hazards frailty models for lifetime data to allow a negative bi-nomial, Poisson, Geometric or other discrete distribution of the frailty variable. This might represent, for example, the unknown number of flaws in an item under test.
Crowder, Martin   +2 more
core   +1 more source

Overlapping and Distinct Physical and Biological Phenotypes in Pure Frailty and Obese Frailty

open access: yesBioscience Reports
Abstract Background: Pure frailty and obese frailty are common types of frailty syndrome. However, the overlapping and distinct characteristics between pure frailty and obese frailty remain unclear. This study aims to reveal the overlapping/distinct physical and biological phenotypes of pure frailty and obese frailty, providing ...
Fujue Ji   +3 more
openaire   +2 more sources

Transdisciplinary Research In Frailty: Knowledge Translation To Inform New Models of Care

open access: yes, 2017
Transforming care for frail older adults requires more than rigorous research. While preventing, identifying and managing frailty are critical to reducing the personal and health systems impact of frailty worldwide, collaborative approaches to research ...
Archibald, M.   +3 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

Comparing Virtual and Center Based Cardiac Rehabilitation on Changes in Frailty

open access: yes, 2022
This is a paper-based thesis, however, the manuscript (Chapter 4) has not been submitted to an academic journal at the time of submitting this thesis.Cardiac rehabilitation (CR) is the gold standard for the secondary prevention of cardiovascular disease (
MacEachern, Evan
core  

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

open access: yesAdvanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su   +13 more
wiley   +1 more source

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