Results 111 to 120 of about 5,609,700 (305)

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

The physical frailty phenotype: Not ready for implementation

American Journal of Transplantation, 2022
Aditi Gupta, Jonathan D. Mahnken, Diane M. Cibrik   +2 more
openaire   +2 more sources

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Frailty in older patients with atrial fibrillation in Vietnam: a comparison between the physical frailty phenotype and the Clinical Frailty Scale

BMC Geriatrics
Background There is limited evidence on the prevalence of frailty and its impact on health outcomes in older adults with atrial fibrillation (AF) in Vietnam.
Tan Van Nguyen, Huy Quoc Nguyen, Lilin Chen, Mark Woodward, Tu Ngoc Nguyen   +4 more
doaj   +1 more source

Frailty for cardiovascular risk stratification in CKM syndrome stages 0–3: a UK Biobank prospective cohort study

Frontiers in Cardiovascular Medicine
BackgroundFrailty shares common pathophysiological mechanisms with cardiovascular-kidney-metabolic (CKM) syndrome and may contribute to cardiovascular risk.
Junhong Wang, Ying Zhao, Zongzong Ma
doaj   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Association of physical activity levels with frailty index in elderly Chinese: evidence from the China health and retirement longitudinal study (CHARLS)

BMC Geriatrics
As the global trend of population aging intensifies, frailty among the elderly has emerged as a significant public Health concern. This study examines the relationship between physical activity levels and the Frailty Index in older adults, utilizing data
Qianqian Li, Jiayi Guan, Ronghui Wang
doaj   +1 more source

Intervention for Social Frailty Focusing on Physical Activity and Reducing Loneliness: A Randomized Controlled Trial [PDF]

Aki Gen, Yumi Higuchi, Tetsuya Ueda, Tomoko Hashimoto, Wataru Kozuki, Tatsunori Murakami, Mio Ishigami Graduate School of Rehabilitation Science, Osaka Metropolitan University, Habikino City, Osaka, JapanCorrespondence: Yumi Higuchi, Graduate School of ...
Hashimoto T, Gen A, Higuchi Y, Kozuki W, Ishigami M, Ueda T, Murakami T   +6 more
core  

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Frailty syndrome: an overview

, 2014
Xujiao Chen,1 Genxiang Mao,1 Sean X Leng2 1Department of Geriatrics, Zhejiang Hospital, Hangzhou, People's Republic of China; 2Division of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine ...
Leng SX, Mao GX, Chen XJ
core