Results 91 to 100 of about 2,296,541 (319)

White book on physical and rehabilitation medicine (PRM) in Europe. Chapter 3. A primary medical specialty: The fundamentals of PRM

, 2018
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper deals with the core concepts at the base of the PRM specialty.
Ceravolo Maria Gabriella, European Physical and Rehabilitation Medicine Bodies Alliance   +1 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Objectively assessed physical activity and subsequent health service use of UK adults aged 70 and over:A four to five year follow up study

, 2014
OBJECTIVES: To examine the associations between volume and intensity of older peoples' physical activity, with their subsequent health service usage over the following four to five years.STUDY DESIGN: A prospective cohort design using baseline ...
Thompson, Janice; id_orcid, Joanna Coulson, Stathi, Afroditi; id_orcid, Fox Kenneth, Davis Mark, Thompson, Janice, Ku, Po Wen, Sharp, Debbie, Simmonds, Bethany, Trayers, Tanya, Afroditi Stathi, Ku Po-Wen, Kenneth Fox, Thompson Janice, Stathi Afroditi, Janice Thompson, Stathi, Afroditi, Davis, Mark, Selena Gray, Hillsdon Melvyn, Stathi, A, Melvyn Hillsdon, Ku, Po-Wen, Trayers Tanya, Bethany Simmonds, Po-Wen Ku, Debbie Sharp, Simmonds Bethany, Gray Selena, Sharp Debbie, Tanya Trayers, Coulson, Joanna, Fox, Kenneth, Coulson Joanna, Gray, Selena, Mark Davis, Hillsdon, Melvyn   +36 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation [PDF]

, 2016
Achieving functional restoration of diseased or injured tissues is the ultimate goal of both regenerative medicine approaches and physical therapy interventions.
Loghmani, M Terry, Loghmani, M. Terry, Thompson, William R, Warden, Stuart J., Warden, Stuart J, Thompson, William R., Ward, Samuel R., Scott, Alexander, Ward, Samuel R   +8 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Long-term effect of a school-based physical activity program (KISS) on fitness and adiposity in children: a cluster-randomized controlled trial [PDF]

, 2013
BACKGROUND: School-based intervention studies promoting a healthy lifestyle have shown favorable immediate health effects. However, there is a striking paucity on long-term follow-ups.
Rocca, Hans-Peter Brunner-La, Helge Hebestreit, Helge Hebestreit (520030), Probst-Hensch, N., Ernst, Dominique, Rocca Hans-Peter Brunner-La, Zahner, L., Schindler, C, Meyer Ursina, Hebestreit Helge, Dominique Ernst, Willem van Mechelen, Kriemler, Susi, Lukas Zahner (18241), Jardena J Puder, Puder, J.J., Hans-Peter Brunner-La Rocca, Ernst, D., Puder Jardena J., Probst-Hensch, Nicole, Probst-Hensch, N, Probst-Hensch Nicole, Kriemler, S., Dominique Ernst (520029), Susi Kriemler, Brunner-La Rocca, H P, Ursina Meyer, Meyer, U, Puder, J J, Christian Schindler (71594), Jardena J. Puder (520033), Kriemler Susi, Zahner, Lukas, Rocca, H.P.B.L., Hebestreit, H, Christian Schindler, Ernst Dominique, Ernst, D, Willem van Mechelen (17577), Zahner Lukas, van Mechelen, W, Susi Kriemler (18250), Brunner-La Rocca, Hans-Peter, Rocca, Hans-Peter Brunner-La; id_orcid, Meyer, Ursina, Ursina Meyer (520028), Rocca, H.P., Schindler Christian, van Mechelen, W., Hans-Peter Brunner-La Rocca (520031), Meyer, U., Puder, Jardena J., Lukas Zahner, Nicole Probst-Hensch (520032), Hebestreit, Helge, Hebestreit, H., Nicole Probst-Hensch, Schindler, Christian, van Mechelen, Willem, Schindler, C., van Mechelen Willem, Zahner, L   +61 more
core   +1 more source

Socioecological influencers of health-promoting lifestyles in Chinese: a preliminary survey using convenient samples

Frontiers in Public Health
BackgroundHealthy lifestyles are considered important means to reduce the burden of diseases. This cross-sectional study was conducted based on the Ecological Model of Health Behavior (EMHB) to analyze the factors associated with the health-promoting ...
Li Huang, Li Huang, Hansen Li, Haowei Liu, Haodong Tian, Haoyue Luo, Jinlong Wu, Yue Luo, Li Peng, Li Peng, Liya Guo, Liya Guo   +11 more
doaj   +1 more source

Physical Activity and Physical Function [PDF]

Obstetrics and Gynecology Clinics of North America, 2018
Sheila A. Dugan, Kelley Pettee Gabriel, Brittney S. Lange-Maia, Carrie Karvonen-Gutierrez   +3 more
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source