Results 131 to 140 of about 3,167,735 (339)

Functional fitness of older women performing physical activities

Revista Brasileira de Cineantropometria e Desempenho Humano, 2010
O envelhecimento é um processo progressivo e natural e a atividade física vem sendo apontada como uma possibilidade de minimizar o seu impacto e, especialmente, manter a capacidade funcional do idoso por mais tempo. O objetivo do presente estudo foi analisar as modificações do Índice de Aptidão Funcional Geral (IAFG) de idosos participan-tes de um ...
Cipriani, Natália Cristina Santos, Meurer, Simone Teresinha, Benedetti, Tania Rosane Bertoldo, Lopes, Marize Amorim   +3 more
openaire   +4 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Functional Age Predicted by Electronic Short Physical Performance Battery Can Detect Frailty Status in Older Adults

Clinical Interventions in Aging, 2020
Hee-Won Jung, 1 Taeyang Jin, 1 Ji Yeon Baek, 1 Seongjun Yoon, 2 Eunjoo Lee, 1 Jack M Guralnik, 3 Il-Young Jang 1 1Division of Geriatrics, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Dyphi Research Institute, Dyphi ...
Jung HW, Jin T, Baek JY, Yoon S, Lee E, Guralnik JM, Jang IY   +6 more
doaj  

The Relationship of Energy Malnutrition, Skeletal Muscle and Physical Functional Performance in Patients with Stable Chronic Obstructive Pulmonary Disease. [PDF]

Nutrients, 2022
Tomita M, Uchida M, Imaizumi Y, Monji M, Tokushima E, Kawashima M.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Effects on strength of vibratory exercise compared to walking in postmenopausal women [PDF]

, 2008
A major problem associated with advanced adult age is the remarkable decline in functional capacity and the associated loss of independence (1). Muscle strength of the lower extremities is a major neuromuscular determinant of these losses and mobility (2)
Gusi, Narcis, Raimundo, Armando, Tomás-Carús, Pablo   +2 more
core  

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Quantitative Assessment of Children with Osteogenesis Imperfecta [PDF]

, 2016
Assessments of children with Osteogenesis Imperfecta (OI) are typically limited to a physical exam and observations from a clinician during a hospital visit.
Caudill, Angela, Flanagan, Ann, Graf, Adam, Harris, Gerald F., Krzak, Joseph, Smith, Peter   +5 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Editorial: Functioning of individuals with cerebral palsy in the 21st century

Frontiers in Rehabilitation Sciences, 2023
Paula Silva de Carvalho Chagas, Hércules Ribeiro Leite   +1 more
doaj   +1 more source