Results 81 to 90 of about 1,522,598 (263)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Hybrid Model Representation of a TLP Including Flexible Topsides in Non-Linear Regular Waves

open access: yesEnergies, 2014
The rising demand for renewable energy solutions is forcing the established industries to expand and continue evolving. For the wind energy sector, the vast resources in deep sea locations have encouraged research towards the installation of turbines in ...
Christof Wehmeyer   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Failure Mechanism of Sandy Soil Slopes Under High-Angle Normal Bedrock-Fault Dislocation: Physical Model Tests

open access: yesApplied Sciences
Bedrock fault dislocation is a crucial structural factor influencing landslide movement. Accurately predicting the location and scale of rupture zones within a slope body is essential for effective slope construction design and risk mitigation.
Jianke Ma   +6 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

PHYSICAL MODELLING AND TESTING OF AN ADVANCED GAS COOLED REACTOR CORE MODEL

open access: yes, 2017
Advanced Gas Cooled Reactor (AGR) cores are multi-layered arrays of graphite components whose geometry and mechanical properties change under prolonged exposure to neutron irradiation. The presence of cracked components in the arrays later in their operational life may cause disruption of core geometry with implications for fuel cooling and control rod
Oddbjornsson, Olafur   +8 more
openaire   +2 more sources

Study on the Mechanism of Landslide Promotion of Expansive Soil Under the Combined Action of Rainfall and Reservoir Water

open access: yes工程科学与技术
ObjectiveThe widespread occurrence of expansive soil landslides poses a significant threat to the long-term stability and safe operation of the Danjiangkou Reservoir.
HUANG Xiaohu   +5 more
doaj  

Experimental Study on the Hydraulic Characteristics and Shape Optimization of Ship Lock Water Conveyance Systems

open access: yesJournal of Marine Science and Engineering
To enhance the passing capacity of the Bailongtan Ship Lock on the Hongshui River, this study focused on the design scheme of its water conveyance system reconstruction and expansion project.
Yu Duan   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy