Results 111 to 120 of about 1,852,356 (316)

Soil Moisture Monitoring Method and Data Products: Current Research Status and Future Development Trends

open access: yesRemote Sensing
Soil moisture (SM) is a key variable regulating land–atmosphere energy exchange, hydrological processes, and ecosystem functioning. Though important, there are still unresolved problems in accurate SM monitoring and the practical application and ...
Ruihao Liu   +3 more
doaj   +1 more source

The General Health Questionnaire-28 (GHQ-28) as an outcome measurement in a randomized controlled trial in a Norwegian stroke population

open access: yesBMC Psychology, 2019
Background Several studies have documented the variety of post-stroke psychosocial challenges, which are complex, multifaceted, and affect a patient’s rehabilitation and recovery.
Ellen G. Hjelle   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Physical parameters and basis transformations in the two-Higgs-doublet model

open access: yes, 2008
A direct connection between physical parameters of general two-Higgs-doublet model (2HDM) potentials after electroweak symmetry breaking (EWSB) and the parameters that define the potentials before EWSB is established.
Nishi, C. C.   +2 more
core   +1 more source

Scattering spectra models for physics

open access: yesPNAS Nexus
Abstract Physicists routinely need probabilistic models for a number of tasks such as parameter inference or the generation of new realizations of a field. Establishing such models for highly non-Gaussian fields is a challenge, especially when the number of samples is limited.
Sihao Cheng   +4 more
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Physical Model of the Reeb Foliation

open access: yesAxioms
In this paper, after explaining some basic aspects of the modern theory of foliations with the aim of describing the celebrated Reeb foliation, we propose the first construction of a comprehensive physical model of it. The construction of the model is achieved through an implementation of geometric methods for 3D printing.
Bande, Gianluca, Franzoni, Gregorio
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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