Results 81 to 90 of about 1,670,440 (312)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Physical and Geotechnical Properties of Tropical Peat and Its Stabilization [PDF]

, 2018
The chapter presents the physical and engineering properties of tropical peat treated with various types of stabilizers. Quick lime (QL), fly ash (FA), and ordinary Portland cement (OPC) were used as stabilizers. The amounts of QL, FA, and OPC added with
Kolay, Prabir K, Prabir K. Kolay, Siti Noor Linda, Taib, Siti Noor Linda Taib   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Effects of Gamma-Irradiation on the Antioxidant Potential of Traditional Bulgarian Teas

Natural Product Communications, 2017
Food irradiation technologies are used to reduce the risk of food borne diseases by eliminating pathogenic microorganisms, prolonging shelf life and reducing storage losses by delaying ripening, germination or sprouting.
Michał Adam Janiak, Adriana Slavova-Kazakova, Magdalena Karamać, Vessela Kancheva, Anastasiya Terzieva, Milena Ivanova, Tsvetelin Tsrunchev, Ryszard Amarowicz   +7 more
doaj   +1 more source

Antioxidant Activity of Flaxseed Extracts in Lipid Systems

Molecules, 2015
The aim of this work was to compare the antioxidant activity of the extract of flaxseed and its alkaline hydrolysate in two model systems: lipid autoxidation of triacylglycerols of sunflower oil (TGSO)—in a homogeneous lipid media and during β-carotene ...
Adriana Slavova-Kazakova, Magdalena Karamać, Vessela Kancheva, Ryszard Amarowicz   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Physical properties of CeIrSi with trillium-lattice frustrated magnetism [PDF]

, 2019
Magnetic (χ), transport (ρ), and heat capacity (Cm) properties of CeIrSi are investigated to elucidate the effect of geometric frustration in this compound with trillium type structure because, notwithstanding its robust effective moment, μeff ≈ 2.46 μB,
Zeiringer, Isolde, Rogl, Peter Franz, Bauer, Ernst, Michor, Herwig; orcid:, Kneidinger, Friedrich, Sidorenko, Andrey, Sereni, J.G.   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Physical properties of sediment core SO93-51KL [PDF]

, 2003
Physical properties of sediment core SO93 ...
Wiedicke-Hombach, Michael, Erlenkeuser, Helmut, Michael Wiedicke-Hombach (6973556), Helmut Erlenkeuser (7886135), Kudrass, Hermann-Rudolph, Weber, Michael E, Hermann-Rudolph Kudrass (6982712), Michael E Weber (6962675)   +7 more
core   +1 more source