Results 91 to 100 of about 3,747,500 (296)

Effects of Different Types of Exercise Training on the Cortisol Awakening Response in Children

open access: yesFrontiers in Endocrinology, 2019
Context: Due to great variability of the hypothalamus-pituitary-adrenal (HPA)-axis, research has to produce better-controlled findings to make a more meaningful statement regarding the effect of exercise training (ET) on the cortisol awakening response ...
Mirko Wegner   +4 more
doaj   +1 more source

The development of creep damage constitutive equations for low Cr-Mo alloy steel and its weldment at low stress [PDF]

open access: yes, 2013
The ultimate objective of this research project is to develop creep damage constitutive equations for low Cr-Mo alloy and its weldment under low stress (0.2-0.4 yield stress,σ_Y).
Lu, Zhongyu, Xu, Qiang, Xu, Qihua
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Assessment of Fertility in Female Offspring of Stressed Male Rats Treated with Sulpiride

open access: yesJournal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Chronic stress has detrimental effects on reproductive system. Offspring are likely to be vulnerable to adverse effects from antipsychotic medication and stress transmitted through gonads and gametes.
Shahla Amiri   +2 more
doaj  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Gender Variations of Physiological and Psychological Stress among Police Officers [PDF]

open access: yes
This paper analyses the effect of gender on reported and perceived levels of stress through examination of both the physical and psychological indicators.
Benno Torgler   +2 more
core  

The Impact of Community Based Adventure Therapy on Stress and Coping Skills in Adults. [PDF]

open access: yes, 2015
Stress and coping skills are among the most essential components of the mental health counseling field. The use of coping skills (e.g., meditation, physical activities, appropriate uses of leisure) has been identified as an effective strategy for stress ...
Gass, Michael A.   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Relationship of Physical stress and Hypertension among Cardiovascular Disease Patients

open access: yesInternational Journal of Endorsing Health Science Research, 2016
Objective: The aim of the study is to find out amount of physical stress among cardiovascular disease (CVD) patients and its relation with hypertension.
Safdar Ali   +6 more
doaj   +1 more source

Impact of Physical Activity on Stress Levels and Methadone Maintenance Treatment Outcomes [PDF]

open access: yes, 2018
Introduction: While the opioid epidemic has continued to intensify over the last decade, unfortunately the likelihood of achieving stable long-term abstinence using methadone maintenance treatment (MMT) remains as low as 60 percent.
Matta, Praneeja, Sterling, PhD, Robert
core   +1 more source

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