Results 81 to 90 of about 1,165,212 (259)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Psychological strain between nurses

open access: yesCentral European Journal of Nursing and Midwifery, 2015
Aim: The aim of the study was to identify differences in perception of work (mental) workload among nurses providing acute and chronic nursing care. Design: Study design is cross-sectional and descriptive.
Andrea Obročníková   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Associations of deep sleep and obstructive sleep apnea with family relationships, life satisfaction, and physical stress experience in children: a caregiver perspective. [PDF]

open access: yesJ Clin Sleep Med, 2023
Bhushan B   +12 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Psychological peculiarities of the formation and the course of maladaptive states of internship doctors in the aspect of their psychocorrection

open access: yesJournal of Education, Health and Sport, 2016
Tense working conditions unfavorably affect not only the somatic, but also the mental health of people working in conditions of constant neuropsychic and physical stress.
V. V. Vyun
doaj  

Mental, physical, environmental, and financial challenges of students: do challenges and demographic profile affect students’ perceived hope?

open access: yesDiversitas Journal
Studying in a university is one of the most difficult stages in an individual’s professional and personal development. During this stage, the individual experiences myriads of challenges including environmental challenges, financial constraints, mental ...
Jomar Aban   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Workplace accidents in Brazil: analysis of physical and psychosocial stress and health-related factors / Acidentes de trabalho no Brasil: análise do estresse físico, psicossocial e fatores relacionados à saúde

open access: yesRAM. Revista de Administração Mackenzie, 2018
Purpose: To identify the influence of physical and psychosocial stress and health-related factors on the occurrence of work-related accidents, based on the National Health Survey (NHS) conducted in Brazil in 2013, through the execution of a retest in the
Simarly M. Soares   +3 more
doaj  

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