Results 101 to 110 of about 11,574,669 (365)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Understanding and Measuring Psychological Stress using Social Media

open access: yes, 2019
A body of literature has demonstrated that users' mental health conditions, such as depression and anxiety, can be predicted from their social media language.
Buffone, Anneke   +4 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Decision-making in Sport under Mental and Physical Stress

open access: yes, 2015
Background: Successful decision-making in sport requires good decisions to be made quickly, but little is understood about the decision process under stress.
Teri J. Hepler
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging

open access: yesOncoTarget, 2018
Physical exercise is considered to be one of the beneficial factors of a proper lifestyle and is nowadays seen as an indispensable element for good health, able to lower the risk of disorders of the cardiovascular, endocrine and osteomuscular apparatus ...
C. Simioni   +6 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Histological Evaluation of Pancreas Following Early Life Stress in Exposure to Pubertal Stress in Male Rats

open access: yesJournal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Stressful events in early-life induce metabolic disorders in adolescence. The aim of this study was to investigate the effect of early-life stress on number or area of Langerhans islets in exposure to foot-shock and psychological ...
Homeira Zardooz   +2 more
doaj  

Bidirectional relationship of stress and affect with physical activity and healthy eating

open access: yesBritish Journal of Health Psychology, 2019
Objectives Physical activity and healthy eating seem to be protective against experiencing stress and negative affect as well as increase positive affect.
Dana Schultchen   +6 more
semanticscholar   +1 more source

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