Results 81 to 90 of about 10,819,752 (405)

Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]

, 2017
The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica, De Stefano, Maria Egle, Florenzano, Fulvio, Gelfo, Francesca, Manni, Luigi, Nisticã², Robert, Petrosini, Laura, Piccinin, Sonia, Protto, Virginia, Soligo, Marzia   +9 more
core   +2 more sources

Evidence-based Approach to Physical Therapy in Cerebral Palsy

Indian Journal of Orthopaedics, 2019
Physiotherapy plays a key role in the management of cerebral palsy (CP) and comprises of various therapeutic interventions in enhancing the various physiological and functional outcomes.
GShankar Ganesh, SaktiPrasad Das
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Age-related differences in exercise and quality of life among breast cancer survivors [PDF]

, 2010
Purpose: Physical activity has become a focus of cancer recovery research as it has the potential to reduce treatment-related burden and optimize health-related quality of life (HRQoL).
Arndt, BETH NEWMAN, Brady, Brucker, Connell, Coster, Courneya, Courneya, Daley, Di Sipio, Drouin, Hayes, Hayes, Holick, Holmes, Kelsey, Kimsey, King, Kopelman, McNeely, McPherson, Meyerhardt, Milne, Mock, Mutrie, Pinto, Pinto, SANDRA C. HAYES, Schmitz, Schwartz, SHEREE A. HARRISON, Stevinson, Thewes, van Dam, Wenzel   +34 more
core   +2 more sources

Association of Early Physical Therapy With Long-term Opioid Use Among Opioid-Naive Patients With Musculoskeletal Pain

JAMA Network Open, 2018
Key Points Question Is early physical therapy associated with long-term opioid use by patients with musculoskeletal pain? Findings In this cross-sectional analysis of 88 985 patients with shoulder, neck, knee, or low back pain, early physical therapy was
E. Sun, Jasmin Moshfegh, C. A. Rishel, C. Cook, A. Goode, S. George   +5 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Restoring Functional Status: A Long-Term Case Report of Severe Lung and Ventilatory Muscle Pump Dysfunction Involving Recurrent Bacterial Pneumonias [PDF]

, 2012
Background and Purpose: Prolonged mechanical ventilation contributes to immobility and deconditioning making efforts to safely discontinue ventilator support desirable. This case report documents how implementing physical therapy treatment interventions,
Laatsch-Lybeck, Linda Jean, Lipchik, Randolph J, Sobush, Dennis   +2 more
core   +2 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

The effects of hypoxia on muscle deoxygenation and recruitment in the flexor digitorum superficialis during submaximal intermittent handgrip exercise

BMC Sports Science, Medicine and Rehabilitation, 2020
Background Decreased oxygenation of muscle may be accentuated during exercise at high altitude. Monitoring the oxygen saturation of muscle (SmO2) during hand grip exercise using near infrared spectroscopy during acute exposure to hypoxia could provide a ...
Hayley J. Nell, Laura M. Castelli, Dino Bertani, Aaron A. Jipson, Sean F. Meagher, Luana T. Melo, Karl Zabjek, W. Darlene Reid   +7 more
doaj   +1 more source

Physical Therapy and Proper Sleep Positions Lead to Improved Hamstring Flexibility [PDF]

, 2018
Research Question: How effectively can physical therapy and correct sleep positioning improve hamstring flexibility and reduce pain, based on age and everyday ...
Miley, Bailey
core   +1 more source