Results 91 to 100 of about 3,115 (303)

É o naturalismo biológico uma concepção fisicalista?

open access: yesPrincipia: An International Journal of Epistemology, 2012
This paper is concerned with the question as to whether biological naturalism (John Searle’s solution for the mind-body problem) can be construed as a physicalist account of the mind.
Tárik de Athayde Prata
doaj  

A Surprising Closeness in Latin American Academia: Luther and Certain Neurosciences

open access: yesOpen Theology, 2018
The purpose of this paper is to show a surprising coincidence between Lutheran Protestantism and physicalist neurosciences regarding the negation of free will and how this issue can begin to be studied in Latin American academia.
Martínez-Barrera Jorge
doaj   +1 more source

Physics and complexity [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2010
This paper is concerned with complex macroscopic behaviour arising in many-body systems through the combinations of competitive interactions and disorder, even with simple ingredients at the microscopic level. It attempts to indicate and illustrate the richness that has arisen, in conceptual understanding, in methodology and in application, across a ...
openaire   +6 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The possibility of physicalism

open access: yesDementia & Neuropsychologia
Modern science has undermined belief in countless imaginary causalities. What is the nature of the relation between mind and brain? Philosophers have debated the issue for millennia, but it is only in the last twenty years that empirical evidence has ...
Eduardo Giannetti
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Physicalism, not scientism [PDF]

open access: yes, 2018
Although physicalism has been a received view in the philosophical community over the past half-century, scientism is by contrast a much more maligned position.
Ney, Alyssa
core  

Presentism, Passage, Phenomenology and Physicalism

open access: yesManuscrito
Temporal dynamists argue that we should believe that there exists temporal passage because there being passage is the best explanation for the presence of our temporal phenomenology.
Kristie Miller, Jane Weiling Loo
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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