Results 101 to 110 of about 3,115 (303)
A psique ao encontro da matéria: corpo e pessoa no projeto médico-científico de Nise da Silveira
História, Ciências, Saúde: ManguinhosResumo No início do século XX, a psiquiatria brasileira foi caracterizada por controversos métodos de tratamento, como a eletroconvulsoterapia, as psicocirurgias e o coma insulínico. Em 1946, a médica alagoana Nise da Silveira ocupou a linha de frente na
Felipe Sales Magaldi
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Physicalism or Anti-Physicalism: A Disjunctive Account [PDF]
In this paper, we make a case for the disjunctive view of phenomenal consciousness: consciousness is essentially disjunctive in being either physical or non-physical in the sense that it has both physical and non-physical possible instances.
Baysan, Umut, Wildman, Nathan
core
, 2017 Grounding physicalism is the thesis that fundamental physical truths ground every other truth. Ted Sider and Shamik Dasgupta have recently put forward a serious challenge to grounding physicalism.
Kofi, Zachary
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Anomalous monism and mental causality : on the debate of Donald Davidson’s philosophy of the mental
, 2004 The English version of the first chapter of Erwin Rogler and Gerhard Preyer: Materialismus, anomaler Monismus und mentale Kausalität. Zur gegenwärtigen Philosophie des Mentalen bei Donald Davidson und David Lewis (2001) "Anomaler Monismus und Mentale ...
Preyer, Gerhard, Rogler, Erwin
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Unlike standard attempts to address the so-called 'hard problem' of consciousness, which assume our understanding of consciousness is unproblematic, this book begins by focusing on phenomenology and is devoted to clarifying the relations between ...
Hutto, Daniel D.
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