Results 111 to 120 of about 873,832 (312)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

How to Achieve the Physicalist Dream Theory of Consciousness: Identity or Grounding? (2020) [PDF]

open access: yes
I argue for three claims. First, there is a strong argument for identity physicalism (Lewis, Sider, Dorr) over dualism. It does achieve the physicalist dream of a maximally simple and uniform view of reality.
Pautz, Adam
core  

The Idealist View of Consciousness After Death [PDF]

open access: yes, 2016
To make educated guesses about what happens to consciousness upon bodily death, one has to have some understanding of the relationship between body and consciousness during life. This relationship, of course, reflects an ontology.
Kastrup, Bernardo
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Experienced incivility undermines the positive effects of job autonomy on mental and physical health

open access: hybrid, 2023
Andrew R. Timming   +4 more
openalex   +1 more source

Philosophy Without Belief [PDF]

open access: yes, 2019
Should we believe our controversial philosophical views? Recently, several authors have argued from broadly conciliationist premises that we should not. If they are right, we philosophers face a dilemma: If we believe our views, we are irrational.
Barnett, Zach
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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