Results 51 to 60 of about 873,832 (312)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Neuroscience, Spiritual Formation, and Bodily Souls: A Critique of Christian Physicalism [PDF]

open access: yes, 2017
The link between human nature and human flourishing is undeniable. "A healthy tree cannot bear bad fruit, nor can a diseased tree bear good fruit" (Matt. 7:18).
Evans, C. Stephen, Rickabaugh, Brandon
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Reconciliation between the Quinian Physicalism of Science and Tabatabaie’s Theory of the Causal Relation between the Supernatural World and the Nature [PDF]

open access: yesپژوهشنامه فلسفه دین, 2017
Tabatabie is an Islamic philosopher who believes in supernatural world and also believes in the causal relation between supernatural world and the nature.
Nader Shokrollahi
doaj   +1 more source

(WP 2011-02) The Change in Sraffa\u27s Philosophical Thinking [PDF]

open access: yes, 2011
The availability of Piero Sraffa’s unpublished manuscripts and correspondence at Trinity College Library, Cambridge, has made it possible to begin to set out a more complete account of Sraffa’s philosophical thinking than previously could be done with ...
Davis, John
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Realizer-functionalism and Life After Death [PDF]

open access: yesپژوهشنامه فلسفه دین, 2019
In contemporary philosophy of mind, some have tried to reduce mental states to physical and bodily states by proposing a model that draws upon both functionalism and the identity theory; thus, reducing the human person to his/her physical body and ...
Mahdi Ghiasvand
doaj   +1 more source

Phenomenal knowledge why: the explanatory knowledge argument against physicalism [PDF]

open access: yes, 2019
Phenomenal knowledge is knowledge of what it is like to be in conscious states, such as seeing red or being in pain. According to the knowledge argument (Jackson 1982, 1986), phenomenal knowledge is knowledge that, i.e., knowledge of phenomenal facts ...
Mørch, Hedda Hassel
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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