Results 101 to 110 of about 145,897 (292)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The medical approach and the social approach to disability: A descriptive analysis

, 2011
The thesis offers a descriptive analysis of how the “medical approach” to disability and the “social approach” to disability understand and analyse disability as an area of inquiry.
Mauri, Christian John
core  

Impairment of sexual life in patients with psoriasis.

, 2007
BACKGROUND: Sexual life can be severely affected in patients with psoriasis. However, this component is not often assessed by clinicians. OBJECTIVE: To estimate the prevalence of sexual impairment and its degree of association with clinical and ...
Abeni D, Sampogna F, IDI Multipurpose Psoriasis Research on Vital Experiences investigators, Tabolli S, GISONDI, Paolo   +4 more
core   +1 more source

Patient vs. physician narratives on refractive surgery in Turkish YouTube videos: a comparative reflexive thematic analysis

Scientific Reports
Correctable refractive errors are a major, preventable cause of visual impairment. Refractive surgery is widely promoted online, yet how Turkish-language YouTube videos frame benefits, risks, recovery, and long-term outcomes—and how this framing differs ...
Nurcan Gürsoy, Ersan Gürsoy
doaj   +1 more source

Disconnect in Assessments of Autosomal Dominant Polycystic Kidney Disease Burden Between Patients and Physicians: A Survey Study

International Journal of Nephrology and Renovascular Disease, 2021
Myrlene Sanon Aigbogun,1 Dorothee Oberdhan,1 Michael J Doane,2 Jillian Rooney,2 Brian C Inyart,2 Christina S Pao,1 Alexis H Denny3 1Health Outcomes, Otsuka Pharmaceutical Development & Commercialization, Inc., Princeton, NJ, USA; 2Health Outcomes ...
Sanon Aigbogun M, Oberdhan D, Doane MJ, Rooney J, Inyart BC, Pao CS, Denny AH   +6 more
doaj  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Towards mobile health care: Neurocognitive impairment monitoring by BCI-based game

, 2016
A mobile-health solution for neuro-cognitive impairment monitoring based on P300 spatio-temporal characterization achieved by tuned Residue Iteration Decomposition (t-RIDE) is here presented.
Annese, V.F., Mezzina, G., V. F. Annese, G. Mezzina, De Venuto, D., D. De Venuto   +5 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Physician Preferences for Bone Metastasis Drug Therapy in Canada

, 2015
Background: Currently in Canada, several bone-targeted agents (BTAS) with varying characteristics are available for the prevention of skeletal-related events (SRES) in patients with bone metastasis secondary to solid tumours.
Y. Qian, N. Califaretti, J. Arellano, J. Posner, A.B. Hauber, M. Habib, E. Chow, A.F. Mohamed, F. Gatta, J.M. González   +9 more
core   +1 more source

Demographics and Clinical Characteristics among Patients with Distinct Psychosocial Burden Profiles Related to Vitiligo: Results of a Latent Class Analysis

Dermatology and Therapy
Introduction Vitiligo may negatively impact quality of life (QOL). This study aimed to classify patients on the basis of the impact of vitiligo on emotional/psychological and social functioning and describe patient characteristics and patient-reported ...
Kent A. Hanson, Khaled Ezzedine, Jenny Austin, Peter Anderson, Simran Marwaha, Samantha K. Kurosky, Roni Adiri, James Piercy, Ernest H. Law   +8 more
doaj   +1 more source