Results 1 to 10 of about 586,745 (312)

Untargeted Metabolomics and Physicochemical Analysis Revealed the Quality Formation Mechanism in Fermented Milk Inoculated with Lactobacillus brevis and Kluyveromyces marxianus Isolated from Traditional Fermented Milk [PDF]

Foods, 2023
Traditional fermented milk from the western Sichuan plateau of China has a unique flavor and rich microbial diversity. This study explored the quality formation mechanism in fermented milk inoculated with Lactobacillus brevis NZ4 and Kluyveromyces ...
Xiao-Lin Ao, Yi-Mo Liao, Hai-Yan Kang, Hong-Li Li, Tian He, Li-Kou Zou, Shu-Liang Liu, Shu-Juan Chen, Yong Yang, Xing-Yan Liu   +9 more
doaj   +2 more sources

The effect of ammonia activation on the desalination potential of natural zeolite

Chimica Techno Acta, 2023
Despite the abundance of water bodies on Earth, there is a limited amount of potable water. Therefore, the desalination process is of great interest. Adsorption of the main contaminants of saline water (Na+, K+, Cl– ions) is an alternative process of ...
Aruzhan K. Kenessova, Akmaral B. Rakhym, Bagashar B. Zhaksybay, Gulziya A. Seilkhanova   +3 more
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Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Biomolecules, 2021
Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life.
Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda   +6 more
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Analysis of Different Binding Modes for Tiagabine within the GAT-1 Transporter

Biomolecules, 2022
The recently obtained cryo-electron microscopy structure (PDB code: 7SK2) of the human γ-aminobutyric acid transporter type 1 (hGAT-1) in complex with the antiepileptic drug, tiagabine, revealed a rather unexpected binding mode for this inhibitor in an ...
Kamil Łątka, Marek Bajda
doaj   +1 more source

Structure Modeling of the Norepinephrine Transporter

Biomolecules, 2020
The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases. In
Izabella Góral, Kamil Łątka, Marek Bajda   +2 more
doaj   +1 more source

Physicochemical analysis of nucleobase-metal interactions [PDF]

Nucleic Acids Symposium Series, 2002
It is important to know what kinds of chemical bonds are formed between metal ions and nucleic acids. We have studied metal-nucleobase interactions, by using NMR spectroscopy in solution. For the accurate understanding, we tried measurement at low temperature below -30 degrees C.
Yoshiyuki, Tanaka, Atsushi, Toyozawa, Yoshinori, Kondo   +2 more
openaire   +2 more sources

Assessment of Productivity Status Using Carlson’s TSI and Fish Diversity of Goronyo Dam, Sokoto State, Nigeria [PDF]

, 2018
Goronyo Dam is the largest lentic waterbody in Sokoto, it was constructed to serve as flood control and used for irrigation activities. The study was conducted to evaluate productivity status and fish diversity of Goronyo Dam in 2016.
Magami, Ibrahim Muhammad, Mainasara, Muhammad Murtala, Maishanu, Hassan Muhammad   +2 more
core   +6 more sources

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Effective therapy of Alzheimer’s disease (AD) requires treatment with a combination of drugs that modulate various pathomechanisms contributing to the disease.
Natalia Szałaj, Justyna Godyń, Jakub Jończyk, Anna Pasieka, Dawid Panek, Tomasz Wichur, Krzysztof Więckowski, Paula Zaręba, Marek Bajda, Anja Pislar, Barbara Malawska, Raimon Sabate, Anna Więckowska   +12 more
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Guanidines: Synthesis of Novel Histamine H₃R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

Pharmaceuticals, 2023
This study examines the properties of novel guanidines, designed and synthesized as histamine H3R antagonists/inverse agonists with additional pharmacological targets.
Marek Staszewski, Magdalena Iwan, Tobias Werner, Marek Bajda, Justyna Godyń, Gniewomir Latacz, Agnieszka Korga-Plewko, Joanna Kubik, Natalia Szałaj, Holger Stark, Barbara Malawska, Anna Więckowska, Krzysztof Walczyński   +12 more
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Synthesis and Characterization of Mechanically Alloyed Nanostructured (Ti,Cr)C Carbide for Cutting Tools Application

Crystals, 2022
(Ti,Cr)C is a novel additive for high-performance cermets. In this work, a (Ti0.8Cr0.2)C nanostructured solid solution was synthesized via Mechanical Alloying (MA) from the mixture of of Ti, Cr, and C powders.
Mohsen Mhadhbi, Wojciech Polkowski
doaj   +1 more source