Results 1 to 10 of about 22,586,824 (312)
The complex nature of Alzheimer’s disease calls for multidirectional treatment. Consequently, the search for multi-target-directed ligands may lead to potential drug candidates.
Dawid Panek +8 more
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(Ti,Cr)C is a novel additive for high-performance cermets. In this work, a (Ti0.8Cr0.2)C nanostructured solid solution was synthesized via Mechanical Alloying (MA) from the mixture of of Ti, Cr, and C powders.
Mohsen Mhadhbi, Wojciech Polkowski
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Neurodegenerative diseases, e.g., Alzheimer’s disease (AD), are a key health problem in the aging population. The lack of effective therapy and diagnostics does not help to improve this situation.
Dorota Łażewska +13 more
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In this work, impedimetric sensors were developed for the detection of the four WFD heavy metals Pb2+, Cd2+, Hg2+ and Ni2+, by the modification of a gold electrode with four partially biosourced polyphosphine polymers.
Taha Chabbah +10 more
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The pyridinium-2-carbaldoximes with quinolinium carboxamide moiety were designed and synthesised as cholinesterase reactivators. The prepared compounds showed intermediate-to-high inhibition of both cholinesterases when compared to standard oximes. Their
Hyun Myung Lee +13 more
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The inverse correlation observed between Alzheimer’s disease (AD) and cancer has prompted us to look for cholinesterase-inhibiting activity in phenothiazine derivatives that possess anticancer properties.
Jakub Jończyk +6 more
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Helosciadium crassipes Koch (Apiaceae) extracts as natural sunscreen and preservative additives
Recently, ingredients derived from natural sources have gained increasing interest in the cosmetic field due to their low toxicity. Therefore, this study was designed to explore the cosmetic potential of Helosciadium crassipes Koch (Apiaceae) species ...
El-Hani MAKHLOUFI +5 more
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The multitarget-directed ligands demonstrating affinity to histamine H3 receptor and additional cholinesterase inhibitory potency represent a promising strategy for research into the effective treatment of Alzheimer’s disease.
Justyna Godyń +19 more
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An on-Line NMR Chemical Shift Prediction Platform Based on Density Functional Theory
With continuing breakthroughs in computational chemistry theory and substantial improvement of computation hardware performance, great progresses have been made in recent years in first principle-based prediction of 1H and 13C chemical shifts of organic ...
LI Qian, TANG Ya-lin, XIANG Jun-feng
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A Starch-Milk Paste Enables the Incorporation of Ripened Cheese in Novel Fresh Cheese
Research background. Fresh cheese varieties represent an important share of the whole cheese market. Although with great variability in terms of composition and method of preparation, fresh cheese varieties are bland in flavour and their production ...
Elpiniki Palyvou-Gianna +3 more
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