Results 231 to 240 of about 8,732,832 (344)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Comparative study of rebaudioside A and rebaudioside Aα: physicochemical properties and in vivo metabolism. [PDF]

open access: yesNPJ Sci Food
Kim HJ   +12 more
europepmc   +1 more source

Conformal Polymer Electrolyte Enabled by Nitrile Coordination for Long‐Cycle Solid‐State Lithium Metal Batteries

open access: yesAdvanced Functional Materials, EarlyView.
The replacement of α‐H with methyl groups markedly improves the compatibility between the electrolyte and lithium metal, facilitating the formation of a conformal SEI layer that effectively accommodates volume variations in lithium metal during cycling.
Liyuan Huang   +9 more
wiley   +1 more source

From Bug to Feature: Harnessing Cross‐Sensitivity for Multiparametric Luminescence Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Cross‐sensitivity in luminescence sensing is reframed from a limitation into a resource for multiparametric detection. Using ruby microspheres as a model system, cross‐sensitivity is quantitatively assessed and exploited through linear discriminant analysis, enabling simultaneous, correction‐free pressure and temperature sensing with a single ...
Nikita Panov   +5 more
wiley   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

open access: yesAdvanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar   +5 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

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