Results 31 to 40 of about 533,338 (305)

Network Physiology reveals relations between network topology and physiological function

, 2012
The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network.
A Angelone, A Bunde, AC Guyton, AY Schumann, B Podobnik, C Schäfer, C Song, C Zhou, E Bullmore, EA Deitch, FG Lizana, G Klösch, GB West, H Otzenberger, H-S Song, I Capellini, I Dvir, J Hasty, JA Lesku, JM Siegel, JR Banavar, KA Schindler, M Massimini, MEJ Newman, P Tassi, PCh Ivanov, PCh Ivanov, R Albert, R Bartsch, R Downey, R Ferri, R Hegger, R Pastor-Satorras, RJ Williams, S Boccaletti, S Lima, SN Dorogovtsev, SV Buldyrev, US Bhalla   +38 more
core   +1 more source

A Physiologically-Based Pharmacokinetic Simulation to Evaluate Approaches to Mitigate Efavirenz-Induced Decrease in Levonorgestrel Exposure with a Contraceptive Implant

Pharmaceutics
Background: Levonorgestrel implant is a highly effective hormonal contraceptive, but its efficacy may be compromised when used with cytochrome enzyme inducers such as efavirenz. The primary aim of this study was to evaluate methods of mitigating the drug
Lilian W. Adeojo, Rena C. Patel, Nancy C. Sambol   +2 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Espectroscopia no infravermelho próximo para a monitorização da perfusão tecidual Near-infrared spectroscopy for monitoring peripheral tissue perfusion in critically ill patients

Revista Brasileira de Terapia Intensiva, 2011
A espectroscopia no infravermelho próximo (NIRS) tem sido principalmente usada na investigação da oxigenação periférica tecidual de forma não invasiva e contínua.
Alexandre Lima, Jan Bakker
doaj   +1 more source

Whole-brain 3D mapping of oxygen metabolism using constrained quantitative BOLD

NeuroImage, 2022
Quantitative BOLD (qBOLD) MRI permits noninvasive evaluation of hemodynamic and metabolic states of the brain by quantifying parametric maps of deoxygenated blood volume (DBV) and hemoglobin oxygen saturation level of venous blood (Yv), and along with a ...
Hyunyeol Lee, Felix W Wehrli
doaj   +1 more source

Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]

, 2013
Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
core   +1 more source

The impact of high grade glial neoplasms on human cortical electrophysiology [PDF]

, 2017
ObjectiveThe brain's functional architecture of interconnected network-related oscillatory patterns in discrete cortical regions has been well established with functional magnetic resonance imaging (fMRI) studies or direct cortical electrophysiology from
Bandt, S. Kathleen, Breshears, Jonathan D, Bundy, David T, Hacker, Carl D, Leuthardt, Eric C, Pahwa, Mrinal, Roland, Jarod L, Sharma, Mohit, Shimony, Joshua S   +8 more
core   +3 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Radiographic evaluation of the effect of nitric oxide on bone healing: an experimental study

Acta Orthopaedica et Traumatologica Turcica, 2021
Methods:Twenty adult Sprague-Dawley rats were used in a critical-size, segmental femoral defect model. A standard 5 mm segmental defect, approximately twice the diameter of the diaphysis, was created in the middle of the shaft.
Yasemin Baldik, Ufuk Talu, Levent Altinel, Hatice Bilge, Gulcin Aykac Toker   +4 more
doaj  

The Neuroanatomic Basis of the Acupuncture Principal Meridians [PDF]

, 2009
Acupuncture involves treating illness by inserting needles at specified body locations (acupoints). The Principal meridians are pathways that join acupoints with related physiologic effects.
Peter Dorsher
core   +1 more source