Results 81 to 90 of about 668,135 (297)

Corrigendum: Coupling Developmental Physiology, Photoperiod, and Temperature to Model Phenology and Dynamics of an Invasive Heteropteran, Halyomorpha halys [PDF]

, 2017
Anne L. Nielsen, Shi Chen, Shelby J. Fleischer   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Frequent respiratory events in postoperative patients aged 60 years and above

Therapeutics and Clinical Risk Management, 2017
Suzanne JL Broens,1 Xuan He,1 Rachel Evley,2 Erik Olofsen,1 Marieke Niesters,1 Ravi P Mahajan,2 Albert Dahan,1 Monique van Velzen1 1Department of Anesthesiology, Leiden University Medical Centre, Leiden, the Netherlands; 2Nottingham University Hospital ...
Broens SJL, He X, Evley R, Olofsen E, Niesters M, Mahajan RP, Dahan A, van Velzen M   +7 more
doaj  

Electronic fluctuation in physiological solutions: Trimethylamine N-oxide and tert-butyl alcohol [PDF]

, 2022
Nahoko Kuroki, Yukina Uchino, Tamon Funakura, Hirotoshi Mori   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Anatomic and Physiological Bases of Social Blushing: Speculations from Neurology and Psychology [PDF]

, 1993
William D. Cutlip, Mark R. Leary
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Associations Between Daily Heart Rate Variability and Self-Reported Wellness: A 14-Day Observational Study in Healthy Adults

Sensors
Heart rate variability (HRV), particularly the root mean square of successive differences (RMSSD), is widely used as a non-invasive indicator of autonomic nervous system activity and physiological recovery.
James Hannon, Adrian O’Hagan, Rory Lambe, Ben O’Grady, Cailbhe Doherty   +4 more
doaj   +1 more source

Predicting the Disposition of the Antimalarial Drug Artesunate and its Active Metabolite Dihydroartemisinin Using Physiologically-Based Pharmacokinetic Modeling [PDF]

, 2020
Ryan Arey, Brad Reisfeld
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source