Results 111 to 120 of about 166,736,405 (308)

Mobile distributed processing of physiological data [PDF]

open access: yes, 2012
Physiological monitoring can be useful in a number of scenarios to evaluate or diagnose the status of individuals or groups, for health or mental reasons.
Lee, K.   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

National Drugs Advisory Board annual report and accounts, 1994

open access: yes, 1994
The National Drugs Advisory Board was established by the Minister for Health in 1966 by the National Drugs Advisory Board (Establishment) Order 1966 (5.1. No. 163 of 1966) under the Health (Corporate Bodies) Act 1961.
National Drugs Advisory Board (NDAB)
core  

AAS, growth hormone, and insulin abuse: psychological and neuroendocrine effects

open access: yesTherapeutics and Clinical Risk Management, 2008
Michael R Graham1, Peter Evans2, Bruce Davies1, Julien S Baker11Health and Exercise Science Research Unit, Faculty of Health Sport and Science, University of Glamorgan, Pontypridd, Wales, United Kingdom; 2Royal Gwent Hospital, Newport, Gwent, United ...
Michael R Graham   +3 more
doaj  

Anticancer drugs and cardiotoxicity: the role of cardiomyocyte and non-cardiomyocyte cells

open access: yesFrontiers in Cardiovascular Medicine
Cardiotoxicity can be defined as “chemically induced heart disease”, which can occur with many different drug classes treating a range of diseases. It is the primary cause of drug attrition during pre-clinical development and withdrawal from the market ...
Chrysa Koukorava   +7 more
doaj   +1 more source

PHYSIOLOGY AND THE EFFECT OF SOME DRUGS ON OSTEOCLAST

open access: yesJournal of Dentistry Indonesia, 2015
The osteoclast cellular process is essential for bone growth, remodeling, and repair, and is, under normal conditions, tightly coupled to the process of bone formation by the osteoblast. It is the balance that determines skeletal mass and shape at any point in time. Some drugs effect the osteoclast formation and differentiation.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reports of side effects associated with the use of drugs 1977

open access: yes, 1977
The National Drugs Advisory Board received 525 Reports in all during 1977. From these 879 Side-Effects were recorded with the use of drugs during the year. There were 18 cases of Drug Interactions- these are listed separately.
National Drugs Advisory Board (NDAB)
core  

A comprehensive review on the effects of sex hormones on chemotherapy-induced cardiotoxicity: are they lucrative or unprofitable?

open access: yesCardio-Oncology
Chemotherapy is one of the routine treatment for preventing rapid growth of the tumor cells. However, chemotherapeutic agents, especially doxorubicin cause damages to the normal cells especially cardiomyocytes.
Golnaz Kheradkhah   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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