Results 111 to 120 of about 502,898 (305)

Physiological and Histopathological Effects of Two Seed Extracts (Phoenix dactylifera and Raphanus sativus) and L-Carnitine Drug on Semen Quality and Testicular Sexual Hormonal Changes in Adult Male Rabbits [PDF]

, 2021

openalex   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Polysaccharide-Based Approaches for Inflammation Treatment: Anti-Inflammatory Mechanisms, Delivery Approaches and Translational Prospects

Biomolecules
Inflammation is a physiological response of the body to infection and tissue damage; dysregulated inflammatory signaling can cause the initiation and aggravation of a variety of chronic diseases.
Xiaoyu Ren, Yuan Zhou, Fei Liu, Lili Jiang, Ai Yuan, Zhouchunxiao Du, Dezhi Sui   +6 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Physiological correlates of motivational effects on information processing: Study of ERP indicators of drug addiction and response to rehabilitation treatment

, 2008
Samuel Pombo›
openalex   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS XLVI ON THE FUNCTIONAL CORRELATION BETWEEN SALIVARY GLANDS AND OTHER ENDOCRINE ORGANS II THE EFFECTS OF SOME ANTITHYROID DRUGS ON THE SALIVARY GLANDS OF RATS

, 1960
Yosoji Ito, JUN KAWADA, MUNETSUGU KURATA
openalex   +2 more sources

Blocking drug activation as a therapeutic strategy to attenuate acute toxicity and physiological effects of heroin [PDF]

, 2018
Ting Zhang, Xirong Zheng, Kyungbo Kim, Fang Zheng, Chang‐Guo Zhan   +4 more
openalex   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Rapid Sensitization of Physiological, Neuronal, and Locomotor Effects of Nicotine: Critical Role of Peripheral Drug Actions [PDF]

, 2013
Magalie Lenoir, Jingda Tang, Amina S. Woods, Eugene A. Kiyatkin   +3 more
openalex   +1 more source