Results 41 to 50 of about 166,736,405 (308)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The Ethics of “Smart Drugs”: Moral Judgments About Healthy People's Use of Cognitive-Enhancing Drugs [PDF]

open access: yes, 2012
What moral concerns are relevant when judging the use of cognitive-enhancing (CE) drugs by healthy people? University students evaluated competitive fairness, distributive fairness, peer pressure, naturalness, and dosage form.

core   +3 more sources

Modelling the behaviour of physiological processes: On the lack of a scientific basis in medical science

open access: yesCommunicative & Integrative Biology
Physiological regulation is extremely complex and cannot be described by homeostasis, the mathematical model generally used in medical science. Homeostasis is based on assumptions which have never been tested or substantiated and when simulated appears ...
Abraham Peper
doaj   +1 more source

Anti-Obesity Drugs: A Review about Their Effects and Safety [PDF]

open access: yesDiabetes & Metabolism Journal, 2012
The current recommendations for the treatment of obese people include increased physical activity and reduced calories intake. When the behavioral approach is not sufficient, a pharmacologic treatment is recommended.
Jun Goo Kang, Cheol-Young Park
doaj   +1 more source

Androgen Deprivation Therapy for Prostate Cancer: Focus on Cognitive Function and Mood

open access: yesMedicina, 2023
Prostate cancer is the second leading cause of cancer death in men in the United States. Androgen deprivation therapy (ADT) is currently the primary treatment for metastatic prostate cancer, and some studies have shown that the use of anti-androgen drugs
Allison B. Reiss   +6 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Antidiabetic Phytochemicals From Medicinal Plants: Prospective Candidates for New Drug Discovery and Development

open access: yesFrontiers in Endocrinology, 2022
Diabetes, a chronic physiological dysfunction affecting people of different age groups and severely impairs the harmony of peoples’ normal life worldwide.
Safaet Alam   +11 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]

open access: yes, 2009
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
core   +1 more source

Heart protective effects of cardioactive drugs associated with antineoplastic treatment against breast cancer

open access: yes, 2022
The prevalence of breast cancer in women is a fundamental problem in public health worldwide. There is consensual evidence that many chemotherapeutic agents might have harmful effects on the cardiovascular system of patients.
Dalmo Miranda   +11 more
core   +1 more source

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