Results 31 to 40 of about 175,272,373 (206)

Effects of Antidepressant Drugs on the Behavioral and Physiological Responses to Lipopolysaccharide (LPS) in Rodents [PDF]

Neuropsychopharmacology, 2001
Antidepressants produce various immunomodulatory effects, as well as an attenuation of the behavioral responses to immune challenges, such as lipopolysaccharide (LPS). To explore further the effects of antidepressants on neuroimmune interactions, rats were treated daily with either fluoxetine (Prozac) or saline for 5 weeks, and various behavioral ...
R, Yirmiya, Y, Pollak, O, Barak, R, Avitsur, H, Ovadia, M, Bette, E, Weihe, J, Weidenfeld   +7 more
openaire   +2 more sources

Physiological and molecular effects of individual and mixtures of drugs of abuse in

Ecotoxicology and Environmental Safety
Drugs of abuse (DAs) are increasingly detected in surface waters, yet their effects on marine organisms remain poorly understood. This study evaluated the impacts of environmentally relevant concentrations (100 and 1000 ng L⁻¹) of cannabinol, codeine ...
Gustavo Salcedo, Frédéric J.J. Chain, Sheree A. Pagsuyoin   +2 more
doaj   +1 more source

Nephroprotective Plants: A Review on the Use in Pre-Renal and Post-Renal Diseases

Plants, 2022
Kidney diseases are expected to become the fifth leading cause of death by 2040. Several physiological failures classified as pre-, intra-, and post-renal factors induce kidney damage.
Mario Adrián Tienda-Vázquez, Zoé P. Morreeuw, Juan Eduardo Sosa-Hernández, Anaberta Cardador-Martínez, Ernesto Sabath, Elda M. Melchor-Martínez, Hafiz M. N. Iqbal, Roberto Parra-Saldívar   +7 more
doaj   +1 more source

Reports of side effects associated with the use of drugs 1991 [PDF]

, 1991
In order that drugs for therapeutic use should be given under the best and safest circumstances, it is important that practitioners be aware of potential hazards in their use.
National Drugs Advisory Board (NDAB)
core  

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]

, 2009
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
core   +1 more source

Effects of novel antidepressant drugs on mesenchymal stem cell physiology

Biomedicine & Pharmacotherapy, 2019
It is known that users of psychotropic drugs often have weight gain, adverse effects on bone mineral density and osteoporosis, but the molecular basis for these side effects is poorly understood. The aim of this study is to evaluate the effects in vitro of duloxetine (a serotonin and norepinephrine reuptake inhibitor) and fluoxetine (a selective ...
Ferroni, Letizia, Gardin, Chiara, Bellin, Gloria, Vindigni, Vincenzo, Pavan, Chiara, Zavan, Barbara   +5 more
openaire   +4 more sources

The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers [PDF]

, 2013
Sattler S, Sauer C, Mehlkop G, Graeff P. The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers. PLoS ONE. 2013;8(7): e68821.Cognitive enhancement (CE) is the pharmaceutical augmentation of mental abilities (e.g ...
Carsten Sauer, Mehlkop Guido, Sattler, Sebastian ; https://orcid.org/, Peter Graeff (434233), Carsten Sauer (434231), Guido Mehlkop, Guido Mehlkop (434232), Peter Graeff, Sauer, Carsten ; https://orcid.org/, Graeff Peter, Sattler Sebastian, Sebastian Sattler (434230), Sebastian Sattler, Graeff, Peter, Mehlkop, Guido, Sauer Carsten   +15 more
core   +1 more source

Experimental Pharmacology: A Hand-Book of Methods for Studying the Physiological Actions of Drugs

, 1883
EXPERIMENTAL PHARMACOLOGY: A HAND-BOOK OF METHODS FOR STUDYING THE PHYSIOLOGICAL ACTIONS OF DRUGS Experimental Pharmacology: A Hand-Book of Methods for Studying the Physiological Actions of Drugs (-
Hermann, Ludimar
core   +5 more sources

Hydrogen Sulfide in Pharmacotherapy, Beyond the Hydrogen Sulfide-Donors

Biomolecules, 2020
Hydrogen sulfide (H2S) is one of the important biological mediators involved in physiological and pathological processes in mammals. Recently developed H2S donors show promising effects against several pathological processes in preclinical and early ...
Ewelina Zaorska, Lenka Tomasova, Dominik Koszelewski, Ryszard Ostaszewski, Marcin Ufnal   +4 more
doaj   +1 more source

Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists

iScience
Summary: ERBB receptor tyrosine kinases are involved in development and diseases like cancer, cardiovascular, neurodevelopmental, and mental disorders.
Lukša Popović, Jan P. Wintgens, Yuxin Wu, Ben Brankatschk, Sascha Menninger, Carsten Degenhart, Niels Jensen, Sven P. Wichert, Bert Klebl, Moritz J. Rossner, Michael C. Wehr   +10 more
doaj   +1 more source