Results 31 to 40 of about 511,607 (303)

Recent advances in understanding adverse effects associated with drugs targeting the serotonin receptor, 5-HT GPCR

open access: yesFrontiers in Global Women's Health, 2022
It has been acknowledged that more women suffer from adverse effects of drugs than men globally. A group of drugs targeting serotonin [5-hydroxytryptamine] (5-HT) binding G-protein-coupled receptors (GPCRs) have been reported to preferentially affect ...
Isabella Marie Jamu, Haruko Okamoto
doaj   +1 more source

The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers

open access: yes, 2013
Sattler S, Sauer C, Mehlkop G, Graeff P. The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers. PLoS ONE. 2013;8(7): e68821.Cognitive enhancement (CE) is the pharmaceutical augmentation of mental abilities (e.g ...
Carsten Sauer   +15 more
core   +1 more source

Appropriate Prescription of Non-Steroidal Anti-Inflammatory Drugs in Geriatric Patients—A Systematic Review

open access: yesBioChem
The elderly population is growing worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, but their adverse events can pose significant risks. Different NSAID molecules can exhibit varying risk profiles.
Carolina Costa   +5 more
doaj   +1 more source

Effects of Antidepressant Drugs on the Behavioral and Physiological Responses to Lipopolysaccharide (LPS) in Rodents [PDF]

open access: yesNeuropsychopharmacology, 2001
Antidepressants produce various immunomodulatory effects, as well as an attenuation of the behavioral responses to immune challenges, such as lipopolysaccharide (LPS). To explore further the effects of antidepressants on neuroimmune interactions, rats were treated daily with either fluoxetine (Prozac) or saline for 5 weeks, and various behavioral ...
R, Yirmiya   +7 more
openaire   +2 more sources

Nephroprotective Plants: A Review on the Use in Pre-Renal and Post-Renal Diseases

open access: yesPlants, 2022
Kidney diseases are expected to become the fifth leading cause of death by 2040. Several physiological failures classified as pre-, intra-, and post-renal factors induce kidney damage.
Mario Adrián Tienda-Vázquez   +7 more
doaj   +1 more source

Effects of novel antidepressant drugs on mesenchymal stem cell physiology

open access: yesBiomedicine & Pharmacotherapy, 2019
It is known that users of psychotropic drugs often have weight gain, adverse effects on bone mineral density and osteoporosis, but the molecular basis for these side effects is poorly understood. The aim of this study is to evaluate the effects in vitro of duloxetine (a serotonin and norepinephrine reuptake inhibitor) and fluoxetine (a selective ...
Ferroni, Letizia   +5 more
openaire   +4 more sources

Leukotriene Receptor Antagonists and Related Compounds

open access: yesCanadian Respiratory Journal, 1999
Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
doaj   +1 more source

COUGH PHYTOTHERAPY IN CHILDREN

open access: yesПедиатрическая фармакология, 2013
Cough is one of the most widespread causes of outpatient pediatrician’s visits. There has been a notable increase in the use of phytogenic drugs recently, including treatment of respiratory infections in children.
L. R. Selimzyanova   +2 more
doaj   +1 more source

On-Target Side Effects of Targeted Therapeutics of Cancer

open access: yesPathology and Oncology Research, 2022
The concept of precision medicine is based on the identification of hallmarks of cancer to exploit them as drug targets. The basic idea was that in this way the therapeutic modalities will be more effective and the side effects will be less.
József Tímár, Andrea Uhlyarik
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

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