Results 11 to 20 of about 511,607 (303)
Anti-Obesity Drugs: A Review about Their Effects and Safety [PDF]
Diabetes & Metabolism Journal, 2012 The current recommendations for the treatment of obese people include increased physical activity and reduced calories intake. When the behavioral approach is not sufficient, a pharmacologic treatment is recommended.
Jun Goo Kang, Cheol-Young Park
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Journal of Research in Pharmacy Practice, 2012 For many decades, researchers are aware of the importance of circadian rhythm in physiological/biochemical properties and drug metabolism. Chronopharmacology is the study of how the effects of drugs vary with biological timing and endogenous ...
Pinar Erkekoglu, Terken Baydar
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Pharmacology of amphetamine-type designer drugs [PDF]
, 2013 In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
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Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]
, 2009 This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
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The effects of estrogen on targeted cancer therapy drugs
Pharmacological Research, 2022 Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao +4 more
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Arquivos Brasileiros de Cardiologia, 2010 Os anti-inflamatórios não esteroides (AINEs) encontram-se entre os medicamentos mais prescritos em todo o mundo. Essa classe heterogênea de fármacos inclui a aspirina e vários outros agentes inibidores da ciclo-oxigenase (COX), seletivos ou não. Os AINEs
Michel Batlouni
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Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney
Bioactive Materials, 2023 Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the high prevalence and high mortality rate of AKI, the development of drugs to effectively treat AKI is a huge unmet medical need and a research hotspot. Although
Qiaohui Chen +11 more
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Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast [PDF]
, 2008 To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system.
Nislow, Corey +20 more
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Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling [PDF]
, 2015 Novel psychoactive substances are newly used designer drugs ("internet drugs", "research chemicals", "legal highs") potentially posing similar health risks to classic illicit substances. Chemically, many novel psychoactive substances can be classified as
Liechti, Matthias E., Matthias Liechti
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Evaluation of lipid-based formulations of poorly water-soluble drugs in the gastro-intestinal tract using in vitro tests [PDF]
, 2011 Novel active pharmaceutical ingredients are often poorly water-soluble. Such compounds may only partially dissolve or may precipitate during intestinal passage, potentially leading to incomplete drug absorption. Despite the importance of the process, the
Arnold, Yvonne Elisabeth
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