Results 11 to 20 of about 501,884 (263)
The effects of estrogen on targeted cancer therapy drugs
Pharmacological Research, 2022 Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao +4 more
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Arquivos Brasileiros de Cardiologia, 2010 Os anti-inflamatórios não esteroides (AINEs) encontram-se entre os medicamentos mais prescritos em todo o mundo. Essa classe heterogênea de fármacos inclui a aspirina e vários outros agentes inibidores da ciclo-oxigenase (COX), seletivos ou não. Os AINEs
Michel Batlouni
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Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney
Bioactive Materials, 2023 Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the high prevalence and high mortality rate of AKI, the development of drugs to effectively treat AKI is a huge unmet medical need and a research hotspot. Although
Qiaohui Chen +11 more
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Direct but no transgenerational effects of decitabine and vorinostat on male fertility. [PDF]
PLoS ONE, 2015 Establishment and maintenance of the correct epigenetic code is essential for a plethora of physiological pathways and disturbed epigenetic patterns can provoke severe consequences, e.g. tumour formation.
Ruth Kläver +10 more
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Acta Cirúrgica Brasileira, 2008 PURPOSE: To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS: Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming ...
Honório Sampaio Menezes +7 more
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Acta Cirúrgica Brasileira, 2007 PURPOSE: To compare the effects of the antidepressant drugs duloxetine and fluoxetine on depressive behaviors in rodents. METHODS: Eighteen male Wistar rats were given systemic injections of duloxetine, fluoxetine, or saline prior to a Forced Swimming ...
Leandro Ciulla +5 more
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Allowed Drugs in Children’s Sports: Results of a Survey Among Sports Doctors
Педиатрическая фармакология, 2015 Relevance. The reception of various vitamin and mineral supplements, dietary supplements and other approved drugs, which enhance physiological capacities of the body, helps to achieve good results in sports.Object of the survey: to study the opinion of ...
E. G. Vershinin, V. V. Delaryu
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Drug release from matrix tablets: physiological parameters and the effect of food [PDF]
Expert Opinion on Drug Delivery, 2014 As dissolution plays an important and vital role in the drug-delivery process of oral solid dosage forms, it is, therefore, essential to critically evaluate the parameters that can affect this process.The consumption of food as well as the physiological environment and properties of the gastrointestinal tract, such as its volume and composition of ...
Nokhodchi, Ali, Asare-Addo, Kofi
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Prediction of PPAR-α ligand-mediated physiological changes using gene expression profiles
Journal of Lipid Research, 2004 Peroxisome proliferator-activated receptor (PPAR)-α controls the transcription of a variety of genes involved in lipid metabolism and is the target receptor for the hypolipidemic drug class of fibrates.
Klaus Stensgaard Frederiksen +5 more
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From Bench to Bedside: What Do We Know about Imidazothiazole Derivatives So Far?
Molecules, 2023 Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to their outstanding physiological activities. Recently, applying imidazothiazole as the core, researchers have synthesized a series of derivatives with biological ...
Mu Guo, Xiangbin Yu, Yi Zhun Zhu, Yue Yu
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