Results 21 to 30 of about 501,884 (263)

A New Frontier in Epilepsy: Novel Antiepileptogenic Drugs

open access: yesJournal of Pharmacological Sciences, 2006
.: Epilepsy is a hetergenous syndrome characterized by recurrently and repeatedly occurring seizures. Although able to inhibit the epileptic seizures, the currently available antiepileptic drugs (AEDs) have no effects on epileptogenesis. Such AEDs should
Masashi Sasa
doaj   +1 more source

Recent advances in understanding adverse effects associated with drugs targeting the serotonin receptor, 5-HT GPCR

open access: yesFrontiers in Global Women's Health, 2022
It has been acknowledged that more women suffer from adverse effects of drugs than men globally. A group of drugs targeting serotonin [5-hydroxytryptamine] (5-HT) binding G-protein-coupled receptors (GPCRs) have been reported to preferentially affect ...
Isabella Marie Jamu, Haruko Okamoto
doaj   +1 more source

Effects of Antidepressant Drugs on the Behavioral and Physiological Responses to Lipopolysaccharide (LPS) in Rodents [PDF]

open access: yesNeuropsychopharmacology, 2001
Antidepressants produce various immunomodulatory effects, as well as an attenuation of the behavioral responses to immune challenges, such as lipopolysaccharide (LPS). To explore further the effects of antidepressants on neuroimmune interactions, rats were treated daily with either fluoxetine (Prozac) or saline for 5 weeks, and various behavioral ...
R, Yirmiya   +7 more
openaire   +2 more sources

Appropriate Prescription of Non-Steroidal Anti-Inflammatory Drugs in Geriatric Patients—A Systematic Review

open access: yesBioChem
The elderly population is growing worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, but their adverse events can pose significant risks. Different NSAID molecules can exhibit varying risk profiles.
Carolina Costa   +5 more
doaj   +1 more source

Nephroprotective Plants: A Review on the Use in Pre-Renal and Post-Renal Diseases

open access: yesPlants, 2022
Kidney diseases are expected to become the fifth leading cause of death by 2040. Several physiological failures classified as pre-, intra-, and post-renal factors induce kidney damage.
Mario Adrián Tienda-Vázquez   +7 more
doaj   +1 more source

Effects of novel antidepressant drugs on mesenchymal stem cell physiology

open access: yesBiomedicine & Pharmacotherapy, 2019
It is known that users of psychotropic drugs often have weight gain, adverse effects on bone mineral density and osteoporosis, but the molecular basis for these side effects is poorly understood. The aim of this study is to evaluate the effects in vitro of duloxetine (a serotonin and norepinephrine reuptake inhibitor) and fluoxetine (a selective ...
Ferroni, Letizia   +5 more
openaire   +4 more sources

Leukotriene Receptor Antagonists and Related Compounds

open access: yesCanadian Respiratory Journal, 1999
Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
doaj   +1 more source

COUGH PHYTOTHERAPY IN CHILDREN

open access: yesПедиатрическая фармакология, 2013
Cough is one of the most widespread causes of outpatient pediatrician’s visits. There has been a notable increase in the use of phytogenic drugs recently, including treatment of respiratory infections in children.
L. R. Selimzyanova   +2 more
doaj   +1 more source

The Relationship Between Physical Activity and Left Ventricular Remodeling in Childhood Cancer Survivors Treated With Anthracyclines: A Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan   +15 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

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