Results 21 to 30 of about 166,736,405 (308)

A New Frontier in Epilepsy: Novel Antiepileptogenic Drugs

open access: yesJournal of Pharmacological Sciences, 2006
.: Epilepsy is a hetergenous syndrome characterized by recurrently and repeatedly occurring seizures. Although able to inhibit the epileptic seizures, the currently available antiepileptic drugs (AEDs) have no effects on epileptogenesis. Such AEDs should
Masashi Sasa
doaj   +1 more source

Recent advances in understanding adverse effects associated with drugs targeting the serotonin receptor, 5-HT GPCR

open access: yesFrontiers in Global Women's Health, 2022
It has been acknowledged that more women suffer from adverse effects of drugs than men globally. A group of drugs targeting serotonin [5-hydroxytryptamine] (5-HT) binding G-protein-coupled receptors (GPCRs) have been reported to preferentially affect ...
Isabella Marie Jamu, Haruko Okamoto
doaj   +1 more source

Pharmacology of amphetamine-type designer drugs [PDF]

open access: yes, 2013
In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
core   +1 more source

Nephroprotective Plants: A Review on the Use in Pre-Renal and Post-Renal Diseases

open access: yesPlants, 2022
Kidney diseases are expected to become the fifth leading cause of death by 2040. Several physiological failures classified as pre-, intra-, and post-renal factors induce kidney damage.
Mario Adrián Tienda-Vázquez   +7 more
doaj   +1 more source

Appropriate Prescription of Non-Steroidal Anti-Inflammatory Drugs in Geriatric Patients—A Systematic Review

open access: yesBioChem
The elderly population is growing worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, but their adverse events can pose significant risks. Different NSAID molecules can exhibit varying risk profiles.
Carolina Costa   +5 more
doaj   +1 more source

Leukotriene Receptor Antagonists and Related Compounds

open access: yesCanadian Respiratory Journal, 1999
Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
doaj   +1 more source

COUGH PHYTOTHERAPY IN CHILDREN

open access: yesПедиатрическая фармакология, 2013
Cough is one of the most widespread causes of outpatient pediatrician’s visits. There has been a notable increase in the use of phytogenic drugs recently, including treatment of respiratory infections in children.
L. R. Selimzyanova   +2 more
doaj   +1 more source

Drug release from matrix tablets: physiological parameters and the effect of food [PDF]

open access: yesExpert Opinion on Drug Delivery, 2014
As dissolution plays an important and vital role in the drug-delivery process of oral solid dosage forms, it is, therefore, essential to critically evaluate the parameters that can affect this process.The consumption of food as well as the physiological environment and properties of the gastrointestinal tract, such as its volume and composition of ...
Nokhodchi, Ali, Asare-Addo, Kofi
openaire   +2 more sources

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier   +18 more
wiley   +1 more source

The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers [PDF]

open access: yes, 2013
Sattler S, Sauer C, Mehlkop G, Graeff P. The Rationale for Consuming Cognitive Enhancement Drugs in University Students and Teachers. PLoS ONE. 2013;8(7): e68821.Cognitive enhancement (CE) is the pharmaceutical augmentation of mental abilities (e.g ...
Carsten Sauer   +15 more
core   +1 more source

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