Results 51 to 60 of about 801,084 (264)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Monitoring of sap flow, leaf water potential, stomatal conductance, and latex yield of rubber trees under irrigation management [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2008
To investigate the physiological responses and latex yield of rubber trees under irrigation management, an experiment was established at Songkhla Province, southern Thailand. The sap flow of rubber trees was measured by heat-pulse technique.
Prapaporn Tongsawang, Sayan Sdoodee
doaj  

Fluid flow to mimic organ function in 3D in vitro models

APL Bioengineering, 2023
Many different strategies can be found in the literature to model organ physiology, tissue functionality, and disease in vitro; however, most of these models lack the physiological fluid dynamics present in vivo.
Yago Juste-Lanas, Silvia Hervas-Raluy, José Manuel García-Aznar, Alejandra González-Loyola   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Towards a physics informed digital twin to predict cerebral blood flow and cerebral vascular regulation

npj Digital Medicine
Cerebral blood flow is essential for brain function and is governed by cerebral perfusion pressure and physiological mechanisms collectively referred to as cerebral vascular regulation (CVR).
Jennifer K. Briggs, J. N. Stroh, Soojin Park, Brandon Foreman, Michael M. Tymko, Jay Carr, Melike Sirlanci, Philip N. Ainslie, Richard K. P. Benninger, Tellen D. Bennett, David J. Albers   +10 more
doaj   +1 more source

Alterations in venous blood flow of lower uterus segment and cervix of uterus at physiological course of preliminary period [PDF]

Саратовский научно-медицинский журнал, 2012
Research objective. The objective of this research is the study of venous blood flow parameters of lower uterus segment and cervix of uterus at the physiological course of preliminary period. Material and methods. The study was based on the investigation
Chekhonatskaya М.L, Yannaeva N.£., Grishaeva L.A., Rogozhina I.£., Prodanova E.V., Bakhmach V.O.   +5 more
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source