Results 81 to 90 of about 1,543,308 (302)

Measuring Flow: Refining Research Protocols That Integrate Physiological and Psychological Approaches

Human Behavior and Emerging Technologies
Measuring flow, an optimal mental state defined by intense focus and immersion, can provide valuable insights into research on human engagement. However, a review of 69 studies identified significant methodological issues that could be undermining ...
Martin Wonders, Dan Hodgson, Nicola Whitton   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Physiological predictors Of peak inspiRatory flow using Observed lung function resultS (POROS): evaluation at discharge among patients hospitalized for a COPD exacerbation

International Journal of COPD, 2018
David B Price,1,2 Sen Yang,1 Simon Wan Yau Ming,1 Antony Hardjojo,1 Claudia Cabrera,3,4 Andriana I Papaioannou,5 Stelios Loukides,5 Vicky Kritikos,6 Sinthia Z Bosnic-Anticevich,6 Victoria Carter,7 Paul M Dorinsky8 1Observational and Pragmatic Research ...
Price DB, Yang S, Wan Yau Ming S, Hardjojo A, Cabrera C, Papaioannou AI, Loukides S, Kritikos V, Bosnic-Anticevich SZ, Carter V, Dorinsky PM   +10 more
doaj  

Monitoring of sap flow, leaf water potential, stomatal conductance, and latex yield of rubber trees under irrigation management [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2008
To investigate the physiological responses and latex yield of rubber trees under irrigation management, an experiment was established at Songkhla Province, southern Thailand. The sap flow of rubber trees was measured by heat-pulse technique.
Prapaporn Tongsawang, Sayan Sdoodee
doaj  

Fluid flow to mimic organ function in 3D in vitro models

APL Bioengineering, 2023
Many different strategies can be found in the literature to model organ physiology, tissue functionality, and disease in vitro; however, most of these models lack the physiological fluid dynamics present in vivo.
Yago Juste-Lanas, Silvia Hervas-Raluy, José Manuel García-Aznar, Alejandra González-Loyola   +3 more
doaj   +1 more source

Anatomy and physiology of coronary blood flow [PDF]

Journal of Nuclear Cardiology, 2010
Regional myocardial blood flow can now be measured noninvasively in units of milliliters blood per minute per gram myocardium. These noninvasive measurements are not confined to a specific imaging modality but are available with MRI, CT, and PET, although, thus far, most investigations of the coronary circulation in humans have employed PET flow ...
openaire   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Alterations in venous blood flow of lower uterus segment and cervix of uterus at physiological course of preliminary period [PDF]

Саратовский научно-медицинский журнал, 2012
Research objective. The objective of this research is the study of venous blood flow parameters of lower uterus segment and cervix of uterus at the physiological course of preliminary period. Material and methods. The study was based on the investigation
Chekhonatskaya М.L, Yannaeva N.£., Grishaeva L.A., Rogozhina I.£., Prodanova E.V., Bakhmach V.O.   +5 more
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

An improved model for reduced-order physiological fluid flows

, 2012
An improved one-dimensional mathematical model based on Pulsed Flow Equations (PFE) is derived by integrating the axial component of the momentum equation over the transient Womersley velocity profile, providing a dynamic momentum equation whose ...
San, Omer, Staples, Anne E.
core   +1 more source