Results 151 to 160 of about 3,079,511 (339)

A Multi-Epiphysiological Indicator Dog Emotion Classification System Integrating Skin and Muscle Potential Signals

open access: yesAnimals
This study introduces an innovative dog emotion classification system that integrates four non-invasive physiological indicators—skin potential (SP), muscle potential (MP), respiration frequency (RF), and voice pattern (VP)—with the extreme gradient ...
Wenqi Jia   +4 more
doaj   +1 more source

The electrochemistry of a gelatin modified gold electrode [PDF]

open access: yes, 2011
This paper discusses the electrochemical behaviour of gelatin coated gold electrodes in physiological pH conditions in a potential window -1.5 till 1.0 V vs SCE by performing cyclic voltammetry. A comparison is made between gelatin A and gelatin B, which
Adriaens, Mieke   +5 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Overtraining and exercise motivation: A research prospectus [PDF]

open access: yes
The problems of exercise overtraining has recently become one of great interest to professionals in the field of human performance assessment. Quite obviously, the ultimate goal of the training process is to improve physical performance.
Hackney, Anthony C.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Classification of artificially aged lentil seeds using Fourier transform near-infrared spectroscopy

open access: yesPesquisa Agropecuária Tropical
Seed deterioration is among the main causes of loss in physiological potential. This study aimed to investigate the potential of Fourier transform near-infrared (FT-NIR) spectroscopy to classify lentil seeds subjected to artificial aging at 41 ºC and 100
Marcelo Augusto Rocha Limão   +5 more
doaj   +1 more source

Unveiling Cocoyam Potentials: Physiology and Agronomy

open access: yesNigeria Agricultural Journal, 2023
Cocoyam is one of the world's oldest food crops grown purposely for food. Though commonly produced by smallholder, resource-limited and mostly female farmers, it plays important roles in nutrition, food security and agrobiodiversity in Africa. However, it has been identified as an underutilized crop that may suffer genetic erosion and an uncertain ...
openaire   +1 more source

Degeneration and regeneration of peripheral nerves: role of thrombin and its receptor PAR-1 [PDF]

open access: yes, 2017
The peripheral nervous system has a striking regeneration potential and after damage extensive changes in the differentiation state both of the injured neurons and of the Schwann cells are observed.
Artico, M.   +7 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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