Results 211 to 220 of about 3,860,015 (301)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Down-Regulation of Disgust by Implementation Intentions: Experiential and Physiological Concomitants

, 2015
Patrick Gomez, Urte Scholz, Brigitta Danuser   +2 more
openalex   +2 more sources

Handbook of Sensory Physiology

, 1975
M. Sanders
semanticscholar   +1 more source

Microglia in Physiology and Disease.

Annual Review of Physiology, 2017
S. Wolf, H. Boddeke, H. Kettenmann
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Review on Effect of Shade Tree on Microclimate, Growth and Physiology of Coffee Arabica: In case of Ethiopia

, 2019
Abebe Assefa, Abebe Assefa Gobena, J Avelino, H Zelaya, A Merlo, A Pineda, M Ordonez, S Savary, J Avelino, S Cabut, B Barboza, M Barquero, R Alfaro, C Esquivel, J Durand, C Cilas, V Barradas, L Fanjul, G Bartlett, W Remphrey, A Baggio, P Caramori, A Androcioli Filho, L Montoya, J Beer, R Muschler, D Kass, E Somarriba, M Campanha, R Silva, G Freitas, H Martinez, S Gracia, F Fing, M Campanha, M Cannell, A Chaves, A Ten-Caten, H Pinheiro, A Ribeiro, F Damatta, S Chris, F Da Matta, M Maestri, F Damatta, N Dao, J Fahl, M Carelli, J Vega, A Magalhaes, G Farquhar, T Sharkey, N Franck, P Vaast, N Franck, N Franck, P Vaast, M Genard, J Dauzat, D Friend, L Jassogne, P Lderach, P Van Asten, D Gates, E Garnier, B Shipley, C Roumet, G Laurent, G Gleison, T Gole, M Denich, T Demel, P Vlek, S Gulmon, C Chu, A Hernandez, J Cock, M El-Sharkawy, P Huxley, M Kasai, H Kim, D Gregory, M Raymond, C John, M Kitao, T Lie, T Koike, H Tobita, Y Maruyama, D Kumar, D Kumar, L Tieszen, E Lammerts Van Bueren, P Struik, D Lee, B Lin, H Li, Y Yong, B Li, R Jing   +99 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source