Results 91 to 100 of about 2,517,871 (188)

RP-HPLC-fluorescence analysis of aliphatic aldehydes: application to aldehyde-generating enzymes HACL1 and SGPL1

Journal of Lipid Research, 2014
Long-chain aldehydes are commonly produced in various processes, such as peroxisomal α-oxidation of long-chain 3-methyl-branched and 2-hydroxy fatty acids and microsomal breakdown of phosphorylated sphingoid bases.
Serena Mezzar, Evelyn de Schryver, Paul P. Van Veldhoven   +2 more
doaj   +1 more source

Refsum disease diagnostic marker phytanic acid alters the physical state of membrane proteins of liver mitochondria [PDF]

, 1999
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid), a branched chain fatty acid accumulating in Refsum disease to high levels throughout the body, induces uncoupling of rat liver mitochondria similar to non-branched fatty acids (e.g.
Heinz Struy, Struy, Heinz, Schönfeld, Peter, Peter Schönfeld   +3 more
core   +1 more source

Studies on the specificity of unprocessed and mature forms of phytanoyl-CoA 2-hydroxylase and mutation of the iron binding ligands

Journal of Lipid Research, 2005
The mature form of phytanoyl-coenzyme A 2-hydroxylase (PAHX), a nonheme Fe(II)- and 2-oxoglutarate-dependent oxygenase, catalyzes the α-hydroxylation of phytanoyl-CoA within peroxisomes.
Timothy Searls, Danica Butler, Winnie Chien, Mridul Mukherji, Matthew D. Lloyd, Christopher J. Schofield   +5 more
doaj   +1 more source

Conversion of Phytol into Dihydrophytol and Phytanic Acid. [PDF]

Acta Chemica Scandinavica, 1966
E. Jellum, L. Eldjarn, K. Try, Egon Pettersson, Berndt Sjöberg, E. Bunnenberg, Carl Djerassi, Ruth Records   +7 more
openaire   +2 more sources

Infantile phytanic acid storage disease, a disorder of peroxisome biogenesis: a case report

, 1990
The infantile and classic forms of phytanic acid storage disease belong to the newly recognized group of peroxisomal disorders. In this paper we report the full clinical, morphological and biochemical results in a patient with infantile phytanic acid ...
Schutgens, R. B., Steinmann, B., Boltshauser, E., Spycher, M. A., Tager, J. M., Wanders, R. J., van den Bosch, H.   +6 more
core   +1 more source

Mobilization of tissue stores of phytanic acid by plasma exchange in heredopathia atactica polyneuritiformis (Refsum's disease)

, 1985
Plasma exchange (PE) in Refsum's disease is associated with a rapid decrease in plasma phytanic acid levels. Its use in conjunction with a low phytanic acid diet is associated with a stabilization of the neurological picture of the disease and with an ...
Collart, Frédéric, Dratwa, Max, Tielemans, Christian   +2 more
core  

Phytanic acid activates PPARα to promote beige adipogenic differentiation of preadipocytes. [PDF]

J Nutr Biochem, 2019
Wang H, Mao X, Du M.
europepmc   +1 more source

Low Phytanic Acid-Concentrated DHA Prevents Cognitive Deficit and Regulates Alzheimer Disease Mediators in an ApoE^-/- Mice Experimental Model. [PDF]

Nutrients, 2018
Ruiz-Roso MB, Echeverry-Alzate V, Ruiz-Roso B, Quintela JC, Ballesteros S, Lahera V, de Las Heras N, López-Moreno JA, Martín-Fernández B.   +8 more
europepmc   +1 more source

Naturally occurring 3RS, 7R, 11R-phytanic acid suppresses in vitro T-cell production of interferon-gamma. [PDF]

Lipids Health Dis, 2018
Nakanishi T, Motoba I, Anraku M, Suzuki R, Yamaguchi Y, Erickson L, Eto N, Sugamoto K, Matsushita Y, Kawahara S.   +9 more
europepmc   +1 more source

Prevention of vitamin A teratogenesis by phytol or phytanic acid results from reduced metabolism of retinol to the teratogenic metabolite, all-trans-retinoic acid

, 2002
Previous studies in our laboratory showed a synergistic interaction of synthetic ligands selective for the retinoid receptors RAR and RXR in regard to teratogenic effects produced in mice (M. M. Elmazar et al., 2001, Toxicol. Appl. Pharmacol.
Arnhold, Thomas, Nau, Heinz, Elmazar, Mohamed M.   +2 more
core