Results 111 to 120 of about 81,928 (258)

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source

Controlling Growth of Ultrasmall Sub‐10 nm Silver Nanoparticles From Cotinus coggygria Scop. Extract and Evaluation of Its In Vitro Anti‐Breast Cancer, Antioxidant and Antimicrobial Activity

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar, Tuğba Nur Aslan, Suray Pehlivanoğlu, Kübra Ece Coşkuner   +3 more
wiley   +1 more source

Natural Product Communications Special Issue for ISNPF2016

Natural Product Communications, 2017
Dhc Yoshinori Asakawa
doaj   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Morpho‐Anatomical and HPTLC Investigations of Lysimachia nummularia L. (Primulaceae) Grown in Switzerland

Microscopy Research and Technique, EarlyView.
This research provides a complete morphoanatomical description of Lysimachia nummularia, as well as a HPTLC profile. Standard techniques of light and scanning electron microscopies, as well as standard techniques of HPTLC, were used. ABSTRACT Primulaceae are distributed all over the world, encompassing around 2590 species.
Carolina Sabedotti, João Vitor da Costa Batista, Bettina Leonhard, Konrad Urech, Mahsa Ahmadinezhad, Jakob Maier, Stephan Baumgartner, Fabio Boylan, Carla Holandino, Jane Manfron   +9 more
wiley   +1 more source

Dietary Phytochemical Index and Its Relationship With Diminished Ovarian Reserve: Evidence From a Case-Control Study. [PDF]

Endocrinol Diabetes Metab
Khodarahmi M, Askari G, Vajdi M, Mokari-Yamchi A, Ghasemi-Tehrani H, Kalatehjari M, Ghavami A.   +6 more
europepmc   +1 more source

Eco‐Friendly Surfactants From Pithecellobium dulce: Extraction, Characterization and Surface Activity

Journal of Surfactants and Detergents, EarlyView.
Schematic representation of the comprehensive analysis of saponins extracted form of Pithecellobium dulce (Roxb.) Benth. ABSTRACT The widespread use of synthetic surfactants in industrial and domestic applications has raised environmental concerns due to their biodegradability and ecological issues.
Susmita Gudulkar, Bijaideep Dutta, Himanshu Dawda, Usha Mukundan, K. C. Barick   +4 more
wiley   +1 more source