Results 221 to 230 of about 342,916 (292)

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

Phytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan, Xinle Wang, Lu Hao, Xiaoqin Tang, Zhixuan Liu, Long Wang, Xiang Xie, Xiang Li, Chunling Zhao, Yan Li, Xinwu Huang, Yuanzhi Liu, Jianming Wu   +12 more
wiley   +1 more source

Brassicaceae Mustards: Phytochemical Constituents, Pharmacological Effects, and Mechanisms of Action against Human Disease. [PDF]

Int J Mol Sci
Rahman M, Khatun A, Liu L, Barkla BJ.
europepmc   +1 more source

Mogroside V Promotes Brown Adipose Thermogenesis via FTO‐m6A‐LETMD1‐UCP1 Pathway to Combat Obesity

Phytotherapy Research, EarlyView.
Mogroside V (MV) alleviates high‐fat diet‐induced obesity and metabolic dysfunction. Mechanistically, MV suppresses FTO expression, thereby increasing m6A modification of Letmd1 mRNA and enhancing its YTHDC2‐dependent stabilization. Theincreased LETMD1 expression is associated with elevated PGC1α and UCP1 levels, contributing to brown adipocyte ...
Yuan‐hai Sun, Ling‐huan Li, Ya‐qian Feng, Teng‐jiao Zhao, Min‐you Qi, Han‐bing Li   +5 more
wiley   +1 more source

Phytochemical constituents analysis in laminaria digitata for Alzheimer's disease: molecular docking and in-silico toxicity approach. [PDF]

Commun Integr Biol
Adella Putri AD, Sembiring MH, Tuba S.
europepmc   +1 more source

Phytochemical Constituents of the Leaves of Landolphia owariensis

Tropical Journal of Natural Product Research, 2019
Nneka Ibekwe, Victor Akoje, John Igoli
openaire   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Health-Promoting Effects, Phytochemical Constituents and Molecular Genetic Profile of the Purple Carrot 'Purple Sun' (Daucus carota L.). [PDF]

Nutrients
Maresca V, Capasso L, Rigano D, Stornaiuolo M, Sirignano C, Piacente S, Cerulli A, Marallo N, Basile A, Nebbioso A, Giordano D, Facchiano A, De Masi L, Bontempo P.   +13 more
europepmc   +1 more source

Fingered Citron Extract Ameliorates Diabetes‐Related Depression via Targeting SRC‐Mediated Insulin Signaling and Neuroinflammation

Phytotherapy Research, EarlyView.
ABSTRACT Diabetes‐related depression (DD) is a challenging comorbidity characterized by self‐reinforcing interactions between metabolic dysfunction and affective disturbance, while conventional antidepressants and glucose‐lowering drugs often yield suboptimal outcomes with adverse effects.
Shun Guo, Tao Yan, Zhuowen Bai, Yuzheng Han, Mengjie Yang, Yajun Zhang   +5 more
wiley   +1 more source

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source